Calcium Phosphate Excipients for Tablet and Capsule Products
As a market leader in speciality phosphates, Chemische Fabrik Budenheim is dedicated to providing innovative calcium phosphates used as excipients and calcium sources in pharmaceutical and nutraceutical formulations.
Budenheim serves the worldwide pharmaceutical and nutraceutical industries with the maximum value in quality, service and innovation. Products include calcium phosphates for wet granulation and for direct compression in pharmaceutical and nutraceutical applications.
Calcium phosphates for direct compression
We offer various types of calcium phosphates for direct compression. These differ in bulk density and particle size and are marketed under the following brand names:
- DI-CAFOS® – dicalcium phosphate anhydrous and di-hydrate
- TRI-CAFOS® – tricalciumphosphate
Directly compressible DCPA
DI-CAFOS A 60 is a unique, innovative, directly compressible DCP anhydrous grade (DCPA). It exhibits a bulk density of 1,300g/l to 1,400g/l, which is significantly higher than the 700g/l to 800g/l typically found with other commercial grades of directly compressible DCPA.
DI-CAFOS A 60 allows pharmaceutical and nutraceutical formulators the flexibility to choose between creating smaller tablets while maintaining the same calcium and phosphorus content, or keeping tablet sizes constant while increasing the calcium and phosphorus content on the label.
In addition to excellent flowing and tabletting properties, DI-CAFOS A 60 also exhibits other important features resulting from the high bulk density, such as:
- Bigger batch size
- Faster discharging during tabletting or capsule-filling process
- Higher production throughput
Our calcium phosphates fulfil all the requirements of major pharmacopeias (e.g. USP, Pharm. Eur. (PE)) and food regulations (e.g. FCC, EC/96/77).
Budenheim was one of the first chemical companies in Germany to reach ISO 9001 and 14001 certification. Budenheim has implemented a HACCP system and operates in accordance to current Good Manufacturing Practice (cGMP). One major plant has already been certified in 2009.
The low lead content of our dicalcium and tricalcium phosphates enables customers to formulate calcium supplements in compliance with California Proposition 65.
Phosphates for pharmaceuticals and nutraceuticals
In addition to calcium phosphates, Budenheim offers also a wide range of other products for pharmaceutical and nutraceutical applications, such as:
- Magnesium phosphates
- Ferric pyrophosphates and orthophosphates
- Sodium phosphates
- Potassium phosphates
These are used as excipients, buffers and efficient mineral sources.
Chemische Fabrik Budenheim was founded in 1908 and started with the production of phosphates in 1916. Since 1923, Budenheim has been part of the Oetker Group, one of Germany’s largest privately held conglomerates. Today, the Budenheim Group has production locations in Germany, Spain, Mexico, the US, China and a joint venture for the production of pure phosphoric acid in Morocco.
Via its network of regional sales offices and local distribution partners Budenheim products are marketed on a global scale and are readily available in more than 100 countries.