ACT-10041239 is under clinical development by Idorsia Pharmaceutical and currently in Phase I for Demyelinating Diseases. According to GlobalData, Phase I drugs for Demyelinating Diseases have a 74% phase transition success rate (PTSR) indication benchmark for progressing into Phase II. GlobalData’s report assesses how ACT-10041239’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.

GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.

ACT-10041239 overview

ACT-10041239 is under development for the treatment of multiple sclerosis and other demyelinating diseases. The therapeutic candidate is formulated as hard gelatin capsule and is administered by oral route. It acts by targeting C-X-C chemokine receptor type 7 (CXCR 7).
It was also under development for the treatment of cancer and unspecified immunological disorders.

Idorsia Pharmaceutical overview

Idorsia Pharmaceutical (Idorsia), a subsidiary of Idorsia Ltd, is a biopharmaceutical company. It discovers, develops, and commercializes therapies to treat central nervous system (CNS), cardiovascular, immunological disorders, and orphan diseases. The company’s product portfolio includes Quviviq, a daridorexant, to treat insomnia; Pivlaz, a clazosentan, for the treatment of cerebral vasospasm; and Tryvio, an aprocitentan, for the treatment of uncontrolled hypertension. Idorsia’s pipeline includes various drugs for the treatment of fabry disease, pediatric insomnia, demyelinating diseases, rare lysosomal storage disorders, recent-onset type 1diabetes, immune-mediated disorders, and clostridium difficile infection. The company has a vaccine platform for the development of glycoconjugate vaccines containing synthetic antigenic glycan molecules to prevent infection. It has a presence in Japan, the UK, South Korea, Switzerland, and the US. Idorsia is headquartered in Arlesheim, Basel-Landschaft, Switzerland.

For a complete picture of ACT-10041239’s drug-specific PTSR and LoA scores, buy the report here.

This content was updated on 16 July 2024

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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.