Akebia Therapeutics has been granted a patent for a method to treat anemia related to chronic kidney disease using specific doses of a HIF prolyl hydroxylase inhibitor. The method involves orally administering a compound to patients with anemia. GlobalData’s report on Akebia Therapeutics gives a 360-degree view of the company including its patenting strategy. Buy the report here.
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According to GlobalData’s company profile on Akebia Therapeutics, Peptide pharmacophores was a key innovation area identified from patents. Akebia Therapeutics's grant share as of February 2024 was 38%. Grant share is based on the ratio of number of grants to total number of patents.
Treating anemia with specific doses of hif prolyl hydroxylase inhibitor
A recently granted patent (Publication Number: US11857543B2) discloses a method for treating anemia secondary to or associated with chronic kidney disease. The method involves orally administering a compound known as {[5-(3-chlorophenyl)-3-hydroxypyridine-2-carbonyl]amino}acetic acid to patients with anemia, particularly those with stage 3, 4, or 5 chronic kidney disease or pre-dialysis chronic kidney disease. The compound can be administered once daily and is effective in maintaining hemoglobin levels within a specific range, with adjustments in dosage based on the patient's response.
Furthermore, the patent outlines the administration of the compound in combination with other medicaments, such as iron supplements, to manage anemia effectively. The method includes specific guidelines for adjusting the daily dose of the compound based on changes in hemoglobin levels observed in patients over time. The patent also specifies the dosage form of the compound, with each tablet containing 150 mg of the active ingredient. Overall, the method provides a structured approach to treating anemia in chronic kidney disease patients, offering a potentially effective and tailored treatment regimen to manage this common complication associated with the condition.
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GlobalData Patent Analytics tracks bibliographic data, legal events data, point in time patent ownerships, and backward and forward citations from global patenting offices. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies
