AL-8326 is under clinical development by Advenchen Laboratories and currently in Phase I for Bladder Cancer. According to GlobalData, Phase I drugs for Bladder Cancer have a 75% phase transition success rate (PTSR) indication benchmark for progressing into Phase II. GlobalData’s report assesses how AL-8326’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.
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GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.
AL-8326 overview
AL-8326 is under development for the treatment of advanced solid tumors including glioblastoma multiforme (GBM), small cell lung cancer, renal cell carcinoma, liver cancer, non-small cell lung cancer, pancreatic cancer, ovarian cancer, breast cancer, colon cancer, head and neck cancer, prostate cancer, kidney cancer, bladder cancer, gastrointestinal stromal tumor and cholangiocarcinoma. It is administered through oral route. The drug candidate is a multikinase inhibitor that acts by targeting Aurora B, FGFR (fibroblast growth factor receptor) and VEGFR (vascular endothelial growth factor receptor).
It was under development for the treatment of epithelial ovarian cancer, fallopian tube cancer, or primary peritoneal cancer, endometrial cancer, cervical cancer.
Advenchen Laboratories overview
Advenchen Laboratories is a pharmaceutical company that offers healthcare solutions. The company conducts pharmaceutical research and develops small-molecule cancer drug discovery programs. Its pipeline products include Rivoceranib/Apatinib, AL3818, AL8326, AL2846 and AL58805. Advenchen Laboratories provides services such as producing inhibitors for the treatment of human colon cancer, liver cancer, gastric cancer and lung and breast cancer, among others. It also provides customized chemical intermediate services. The company operates in China and the US. Advenchen Laboratories is headquartered in Moorpark, California, the US.
For a complete picture of AL-8326’s drug-specific PTSR and LoA scores, buy the report here.
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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.
GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.
