The Alpha Galactosidase A pipeline drugs market research report outlays comprehensive information on the Alpha Galactosidase A targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA), and molecule type. GlobalData’s report assesses the drugs in the Alpha Galactosidase A pipeline by therapy areas, indications, stages, MoA, RoA, molecule type and the key players in the development pipeline. Buy the report here.
The report also covers products from therapy areas such as Metabolic Disorders, and Oncology which include the indications Fabry Disease, and Unspecified Cancer. It also reviews key players involved in Alpha Galactosidase A targeted therapeutics development with respective active and dormant or discontinued products.
The Alpha Galactosidase A pipeline targets constitutes close to 25 molecules. Out of which, approximately 23 molecules are developed by companies and the remaining by the universities/institutes. The molecules developed by companies in Phase III, Phase II, Phase I, Phase 0, IND/ CTA Filed, Preclinical, and Discovery stages are 3, 3, 2, 1, 1, 9, and 3 respectively. Similarly, the universities portfolio in Preclinical comprises 1 molecule.
Alpha Galactosidase A overview
Alpha-galactosidase is a glycoside hydrolase enzyme encoded by the GLA gene. This enzyme is a homodimeric glycoprotein that hydrolyses the terminal alpha-galactosyl moieties from glycolipids and glycoproteins. It predominantly hydrolyzes ceramide trihexoside, and it can catalyze the hydrolysis of melibiose into galactose and glucose. Mutations in this gene affect the synthesis and stability of this enzyme which causes Fabry’s disease.
For a complete picture of Alpha Galactosidase A’s drug pipeline, buy the report here.
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