AMT-151 is under clinical development by Multitude therapeutics and currently in Phase I for Malignant Pleural Mesothelioma. According to GlobalData, Phase I drugs for Malignant Pleural Mesothelioma have an 80% phase transition success rate (PTSR) indication benchmark for progressing into Phase II. GlobalData’s report assesses how AMT-151’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.

GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.

AMT-151 overview

AMT-151 is under development for the treatment of solid tumor including endometrial cancer, epithelial ovarian cancer, fallopian tube cancer, primary peritoneal cancer, pancreatic ductal adenocarcinoma, malignant pleural mesothelioma, triple-negative breast cancer (TNBC), lung adenocarcinoma, non-small cell lung cancer (NSCLC) and unspecified indication. The drug candidate is an antibody-drug conjugate (ADC) composed of a monoclonal antibody targeting folate receptor alpha conjugated to an undisclosed cytotoxic agent. It is administered through intravenous route. 

Multitude therapeutics overview

Multitude therapeutics is a Pharmaceuticals and Healthcare company that Develop antibody-drug conjugates. The company is headquartered in Redwood city, California, The U.S.

For a complete picture of AMT-151’s drug-specific PTSR and LoA scores, buy the report here.

This content was updated on 22 April 2024

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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.