Betta Pharmaceuticals has been granted a patent for a bromodomain inhibitor, including specific crystalline forms. The invention covers compositions, formulations, and methods of using and preparing these compounds. GlobalData’s report on Betta Pharmaceuticals gives a 360-degree view of the company including its patenting strategy. Buy the report here.
According to GlobalData’s company profile on Betta Pharmaceuticals, Cancer treatment biomarkers was a key innovation area identified from patents. Betta Pharmaceuticals's grant share as of January 2024 was 28%. Grant share is based on the ratio of number of grants to total number of patents.
Bromodomain inhibitor in crystalline form
A recently granted patent (Publication Number: US11845762B2) discloses a crystalline form of a compound with a specific X-ray powder diffraction pattern, as outlined in claims 1 and 2. The crystalline form is characterized by peaks at 2? values of 13.8±0.2°, 18.9±0.2°, and 26.0±0.2°, and may be anhydrous, as specified in claim 3. This unique crystalline form is utilized in claim 4 to formulate a pharmaceutical composition along with a pharmaceutical acceptable excipient, with a defined weight ratio range in claim 5.
Furthermore, the patent claims encompass a method for treating BET-mediated diseases in a subject by administering the crystalline form of claim 1. The BET-mediated diseases listed include various types of leukemia, lymphoma, solid tumors, and other cancers, as detailed in claim 6. The method specifies the involvement of BRD4 in BET-mediated diseases and is intended for human subjects, as indicated in claims 7 and 8. This patent highlights the potential therapeutic applications of the disclosed crystalline form in targeting BET-mediated diseases, particularly in the treatment of various types of cancer in human patients.
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