BeyondSpring. has been granted a patent for plinabulin polymorphs, specifically a crystalline form of plinabulin monohydrate. The patent includes claims regarding its unique X-ray powder diffraction pattern, which features at least three specific characteristic peaks. GlobalData’s report on BeyondSpring gives a 360-degree view of the company including its patenting strategy. Buy the report here.
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According to GlobalData’s company profile on BeyondSpring, Cancer treatment biomarkers was a key innovation area identified from patents. BeyondSpring's grant share as of July 2024 was 32%. Grant share is based on the ratio of number of grants to total number of patents.
Crystalline form of plinabulin for therapeutic use
The granted patent US12024501B2 presents a series of claims related to various crystalline forms of plinabulin, a compound with potential therapeutic applications. The claims detail specific X-ray powder diffraction patterns characterized by distinct peaks at various 2? angles, which are critical for identifying the crystalline structure of plinabulin. Notably, claims 1 and 8 outline two different crystalline forms, each exhibiting unique diffraction patterns with specified peaks. Additionally, the patent claims include information on the melting points of these forms, with one crystalline form melting at approximately 264°C and another at about 267°C. The differential scanning calorimetry (DSC) thermograms associated with these forms also reveal endothermic peaks, further confirming their distinct thermal properties.
Moreover, the patent encompasses compositions of plinabulin that incorporate excipients, with claims specifying that these compositions contain more than 50% or 75% by weight of the crystalline form of plinabulin. This highlights the potential for formulating plinabulin in various pharmaceutical applications. The claims also emphasize the importance of the crystalline form's stability and purity, which are essential for ensuring the efficacy and safety of the resulting compositions. Overall, the patent provides a comprehensive framework for the characterization and application of plinabulin in medicinal formulations, underscoring its significance in the pharmaceutical landscape.
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GlobalData Patent Analytics tracks bibliographic data, legal events data, point in time patent ownerships, and backward and forward citations from global patenting offices. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies
