BNC-210 is under clinical development by Bionomics and currently in Phase II for Post-Traumatic Stress Disorder (PTSD). According to GlobalData, Phase II drugs for Post-Traumatic Stress Disorder (PTSD) does not have sufficient historical data to build an indication benchmark PTSR for Phase II. GlobalData uses proprietary data and analytics to create drugs-specific PTSR and LoA in the BNC-210 LoA Report. Buy the report here.

GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.

BNC-210 overview

BNC-210 (IW-2143) is under development for the treatment of agitation (anxiety disorder), post-traumatic stress disorder, social anxiety disorder, unspecified CNS diseases and CCK-4 induced panic disorder. The drug candidate is administered through the oral route. BNC-210 acts by targeting neuronal acetylcholine receptor subunit alpha-7 (CHRNA7). It was also under development for the treatment of depression.

Bionomics overview

Bionomics, is a biopharmaceutical company that discovers and develops treatments for cancer, and central nervous system disorders such as anxiety, depression and Alzheimer’s disease. The company provides pipeline products such as BNC210, BNC 105, BNC101 and BNC375, among others. It uses various technology platforms including KV1.3 compound, VDA compound, MultiCore technology and cancer stem cell technology platform for discovering highly active, functional therapeutic antibodies and small molecule candidates that target cancer stem cells, among others. The company conducts clinical studies including post-traumatic stress disorder study, multiple ascending dose study, and generalized anxiety disorder study, dose esclaltion study. Bionomics is headquartered in Thebarton, South Australia, Australia.

For a complete picture of BNC-210’s drug-specific PTSR and LoA scores, buy the report here.

This content was updated on 10 June 2024

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GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.