BXQ-350 is under clinical development by Bexion Pharmaceuticals and currently in Phase I for Chemotherapy Induced Peripheral Neuropathy. According to GlobalData, Phase I drugs for Chemotherapy Induced Peripheral Neuropathy does not have sufficient historical data to build an indication benchmark PTSR for Phase I. GlobalData uses proprietary data and analytics to create drugs-specific PTSR and LoA in the BXQ-350 LoA Report. Buy the report here.
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GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.
BXQ-350 overview
BXQ-350 is under development for the treatment of cancers including glioblastoma, lung squamous cell carcinoma, malignant glioma, pancreatic cancer, prostate cancer, ependymoma, pediatric diffuse intrinsic pontine glioma, diffuse midline glioma (DMG) and other solid tumors and unspecified central nervous system disorders, lysosomal storage disorder and unspecified viral infections. The drug candidate is administered through intravenous injection. The drug candidate is developed based on Dubbed SapC-DOPS technology. BXQ-350 is a nanovesicle formulation of synthetically produced, human lysosomal protein saposin C (sphingolipid activator protein, or SapC, 80 aa) and the phospholipid dioleoylphosphatidylserine (DOPS). BXQ-350 targets phosphatidylserine (PS) lipids.
It was also under development for the treatment of malignant peripheral nerve sheath tumor, head and neck cancer, neuroblastoma, recurrent solid tumors, brain tumor, breast cancer, pineoblasotoma, osteosarcoma.
Bexion Pharmaceuticals overview
Bexion Pharmaceuticals (Bexion) is a clinical-stage biopharmaceutical company that develops a new generation of biologic therapy to treat solid tumor cancers and chemotherapy-induced peripheral neuropathy (CIPN). The company’s lead drug candidate BXQ-350, is a novel S1P modulator that treats cancer. Bexion is headquartered in Covington, Kentucky, the US.
For a complete picture of BXQ-350’s drug-specific PTSR and LoA scores, buy the report here.
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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.
GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.
