The C-X-C Chemokine Receptor Type 2 pipeline drugs market research report outlays comprehensive information on the C-X-C Chemokine Receptor Type 2 targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA), and molecule type. GlobalData’s report assesses the drugs in the C-X-C Chemokine Receptor Type 2 pipeline by therapy areas, indications, stages, MoA, RoA, molecule type and the key players in the development pipeline. Buy the report here.
The report also covers products from therapy areas such as Oncology, Immunology, Respiratory, and Metabolic Disorders which include the indications Solid Tumor, Metastatic Castration-Resistant Prostate Cancer (mCRPC), Inflammation, Autoimmune Disorders, Acute Respiratory Distress Syndrome, Chronic Obstructive Pulmonary Disease (COPD), Obesity, and Type 1 Diabetes (Juvenile Diabetes). It also reviews key players involved in C-X-C Chemokine Receptor Type 2 targeted therapeutics development with respective active and dormant or discontinued products.
The C-X-C Chemokine Receptor Type 2 pipeline targets constitutes close to 18 molecules. Out of which, approximately 18 molecules are developed by companies and the remaining by the universities/institutes. The molecules developed by companies in Phase III, Phase II, Phase I, Preclinical, and Discovery stages are 2, 4, 2, 8, and 2 respectively.
C-X-C Chemokine Receptor Type 2 overview
CXCR2 or Interleukin 8 receptor, beta is a chemokine receptor. It binds to IL8 with high affinity, and transduces the signal through a G-protein-activated second messenger system. This receptor also binds to chemokine (C-X-C motif) ligand 1 and has shown a major role in serum-dependent melanoma cell growth. This receptor mediates neutrophil migration to sites of inflammation. The angiogenic effects of IL8 in intestinal microvascular endothelial cells are found to be mediated by this receptor.
For a complete picture of C-X-C Chemokine Receptor Type 2’s drug pipeline, buy the report here.
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