The C-X-C Chemokine Receptor Type 4 pipeline drugs market research report outlays comprehensive information on the C-X-C Chemokine Receptor Type 4 targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA), and molecule type. GlobalData’s report assesses the drugs in the C-X-C Chemokine Receptor Type 4 pipeline by therapy areas, indications, stages, MoA, RoA, molecule type and the key players in the development pipeline. Buy the report here.
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The report also covers products from therapy areas such as Oncology, Immunology, Respiratory, and Dermatology which include the indications Solid Tumor, Unspecified Cancer, Transplant Rejection, Autoimmune Disorders, Acute Respiratory Distress Syndrome, Idiopathic Pulmonary Fibrosis, Wounds, and Hypertrophic Scars. It also reviews key players involved in C-X-C Chemokine Receptor Type 4 targeted therapeutics development with respective active and dormant or discontinued products.
The C-X-C Chemokine Receptor Type 4 pipeline targets constitutes close to 41 molecules. Out of which, approximately 35 molecules are developed by companies and the remaining by the universities/institutes. The molecules developed by companies in Phase III, Phase II, Phase I, Preclinical, and Discovery stages are 2, 7, 4, 16, and 6 respectively. Similarly, the universities portfolio in Phase I, and Preclinical comprises 1, and 5 molecule.
C-X-C Chemokine Receptor Type 4 overview
C-X-C chemokine receptor type 4 or CD184 is a protein encoded by the CXCR4 gene. It is a receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ion levels and enhancing MAPK1/MAPK3 activation, extracellular ubiquitin, leading to enhanced intracellular calcium ions and reduced cellular cAMP levels. It is involved in hematopoiesis and in cardiac ventricular septum formation. It also plays an essential role in vascularization of the gastrointestinal tract, probably by regulating vascular branching and/or remodeling processes in endothelial cells.
For a complete picture of C-X-C Chemokine Receptor Type 4’s drug pipeline, buy the report here.
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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.
Global Markets Direct’s report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Direct’s proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third-party sources.
Drug profiles featured in the report undergo periodic review following a stringent set of processes to ensure that all the profiles are updated with the latest set of information. Additionally, various dynamic tracking processes ensure that the most recent developments are captured on a real time basis.
