C4 Therapeutics. has filed a patent for tricyclic compounds that degrade neosubstrates to treat disorders like abnormal cellular proliferation, neurodegenerative diseases, and autoimmune diseases. The patent claim focuses on compounds of a specific formula. GlobalData’s report on C4 Therapeutics gives a 360-degree view of the company including its patenting strategy. Buy the report here.

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According to GlobalData’s company profile on C4 Therapeutics, Cancer treatment biomarkers was a key innovation area identified from patents. C4 Therapeutics's grant share as of January 2024 was 11%. Grant share is based on the ratio of number of grants to total number of patents.

Degradation of neosubstrates for treating various disorders

Source: United States Patent and Trademark Office (USPTO). Credit: C4 Therapeutics Inc

The patent application (Publication Number: US20240018118A1) discloses a compound of Formula with specific variations and substitutions outlined in the claims. The compound includes various fused ring structures such as phenyl, heteroaryl, heterocycle, cycloalkyl, and cycloalkenyl, with optional substituents allowed by valence. Additionally, the compound comprises different groups like alkyl, halogen, aryl, and heterocycle, among others, at specific positions within the structure.

Furthermore, the patent application extends to a pharmaceutical composition containing the compound and a pharmaceutically acceptable excipient. It also covers a method for treating medical disorders mediated by cereblon in humans by administering the compound or a pharmaceutically acceptable salt thereof. The disorders targeted include abnormal cellular proliferation, neurodegenerative diseases, and autoimmune diseases, showcasing the potential therapeutic applications of the disclosed compound in various medical conditions.

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GlobalData Patent Analytics tracks bibliographic data, legal events data, point in time patent ownerships, and backward and forward citations from global patenting offices. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies