The Calreticulin pipeline drugs market research report outlays comprehensive information on the Calreticulin targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA), and molecule type. GlobalData’s report assesses the drugs in the Calreticulin pipeline by therapy areas, indications, stages, MoA, RoA, molecule type and the key players in the development pipeline. Buy the report here.
The report also covers products from therapy areas such as Oncology, Ophthalmology, and Gastrointestinal which include the indications Myeloproliferative Disorders, Essential Thrombocythemia, Choroidal Neovascularization, and Inflammatory Bowel Disease. It also reviews key players involved in Calreticulin targeted therapeutics development with respective active and dormant or discontinued products.
The Calreticulin pipeline targets constitutes close to eight molecules. Out of which, approximately five molecules are developed by companies and the remaining by the universities/institutes. The molecules developed by companies in Phase I, Preclinical, and Discovery stages are 2, 1, and 2 respectively. Similarly, the universities portfolio in Preclinical comprises 3 molecule.
Calreticulin overview
Calreticulin is a protein that in humans is encoded by a gene CALR. It is also known as calregulin, calsequestrin-like protein, and endoplasmic reticulum resident protein 60 (ERp60). CALR is involved in a variety of cellular processes mainly in cell adhesion, protein folding quality control and calcium homeostasis. Calreticulin is also found in the nucleus, suggesting that it may have a role in transcription regulation. Systemic lupus erythematosus is associated with increased autoantibody titers against calreticulin. Recurrent mutations in calreticulin have been linked to various neoplasms, including the myeloproliferative type.
For a complete picture of Calreticulin’s drug pipeline, buy the report here.
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