The Caspase 9 pipeline drugs market research report outlays comprehensive information on the Caspase 9 targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA), and molecule type. GlobalData’s report assesses the drugs in the Caspase 9 pipeline by therapy areas, indications, stages, MoA, RoA, molecule type and the key players in the development pipeline. Buy the report here.
The report also covers products from therapy areas such as Oncology, Ophthalmology, Central Nervous System, and Dermatology which include the indications Oncology, Prostate Cancer, Diabetic Retinopathy, Age Related Macular Degeneration, Alzheimer’s Disease, Parkinson’s Disease, Actinic (Solar) Keratosis, and Atopic Dermatitis (Atopic Eczema). It also reviews key players involved in Caspase 9 targeted therapeutics development with respective active and dormant or discontinued products.
The Caspase 9 pipeline targets constitutes close to eight molecules. Out of which, approximately five molecules are developed by companies and the remaining by the universities/institutes. The molecules developed by companies in Filing rejected/ Withdrawn, and Preclinical stages are 1, and 4 respectively. Similarly, the universities portfolio in Preclinical, and Discovery comprises 1, and 2 molecule.
Caspase 9 overview
Caspase-9 is an initiator caspase encoded by the CASP9 gene. Binding of caspase-9 to Apaf-1 leads to activation of the protease which cleaves and activates caspase-3. It is involved in the activation cascade of caspases responsible for apoptosis execution. It promotes DNA damage-induced apoptosis in an ABL1/c-Abl-dependent manner.
For a complete picture of Caspase 9’s drug pipeline, buy the report here.
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