Catalent has patented a naproxen formulation for soft gel dosage units, enhancing stability and bioavailability. The fill formulation includes naproxen, naproxen sodium, polyethylene glycol, propylene glycol, povidone, water, and phenylephrine hydrochloride. The pH ranges from 4 to 6, without a neutralization agent, allowing for higher concentration and smaller dosage unit size. GlobalData’s report on Catalent gives a 360-degree view of the company including its patenting strategy. Buy the report here.
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According to GlobalData’s company profile on Catalent, was a key innovation area identified from patents. Catalent's grant share as of February 2024 was 47%. Grant share is based on the ratio of number of grants to total number of patents.
A recently granted patent (Publication Number: US11896566B2) discloses a softgel dosage form containing a pharmaceutical fill formulation with specific ingredients and ratios. The formulation includes naproxen, naproxen sodium, polyethylene glycol, propylene glycol, povidone, water, and phenylephrine hydrochloride. The total amount of naproxen and naproxen sodium ranges from about 22% to 30% by weight, with a pH of 4 to 6. Importantly, the fill formulation is free of a neutralization agent and has a smaller volume compared to a neutralized naproxen fill composition with an equivalent dose.
Furthermore, the patent also covers a dosage form encapsulating a non-steroidal anti-inflammatory drug (NSAID) suitable for a soft gel capsule. The pharmaceutical fill formulation in this dosage form mirrors the one in the softgel dosage form, emphasizing the specific ratios and ingredients. The formulation's pH ranges from 2 to 8, and it is devoid of a neutralization agent, ensuring its unique composition. With a focus on maintaining specific ratios and ingredients, this patent highlights the innovation in creating dosage forms with precise formulations that offer potential benefits in drug delivery and efficacy.
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GlobalData Patent Analytics tracks bibliographic data, legal events data, point in time patent ownerships, and backward and forward citations from global patenting offices. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies
