The CD40 Ligand pipeline drugs market research report outlays comprehensive information on the CD40 Ligand targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA), and molecule type. GlobalData’s report assesses the drugs in the CD40 Ligand pipeline by therapy areas, indications, stages, MoA, RoA, molecule type and the key players in the development pipeline. Buy the report here.
The report also covers products from therapy areas such as Oncology, Immunology, Central Nervous System, and Genetic Disorders which include the indications Solid Tumor, Pancreatic Cancer, Systemic Lupus Erythematosus, Rheumatoid Arthritis, Multiple Sclerosis, Relapsing Remitting Multiple Sclerosis (RRMS), and Genetic Disorders. It also reviews key players involved in CD40 Ligand targeted therapeutics development with respective active and dormant or discontinued products.
The CD40 Ligand pipeline targets constitutes close to 30 molecules. Out of which, approximately 27 molecules are developed by companies and the remaining by the universities/institutes. The molecules developed by companies in Phase III, Phase II, Phase I, Preclinical, and Discovery stages are 3, 4, 8, 9, and 3 respectively. Similarly, the universities portfolio in Preclinical comprises 3 molecule.
CD40 Ligand overview
CD40 ligand or CD40L is a protein that is primarily expressed on activated T cells and is a member of the TNF superfamily. The CD40-CD40 ligand interaction is crucial to the development of T dependent immune responses. The ligand is expressed on a range of cell types including B cells, granulocytes, macrophages and platelets. T cells expressing CD40L provide signals to B cells that induce proliferation, immunoglobulin class switching, antibody secretion, and rescue from apoptosis at different times during the life of a B cell and also have a role in the development of germinal centres and the survival of memory B cells.
For a complete picture of CD40 Ligand’s drug pipeline, buy the report here.
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