Dimesna is under clinical development by Lantern Pharma and currently in Phase II for Non-Small Cell Lung Cancer. According to GlobalData, Phase II drugs for Non-Small Cell Lung Cancer have a 38% phase transition success rate (PTSR) indication benchmark for progressing into Phase III. GlobalData’s report assesses how Dimesna’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.

GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.

Dimesna overview

Dimesna (BNP7787) is under development for the treatment of relapsed non-small cell lung cancer for never smokers. It is administered by oral or intravenous route. Tavocept (BNP7787) acts by targeting thioredoxin and glutaredoxin systems. It was also under development for the treatment of adenocarcinoma of lungs, metastatic breast cancer, and solid tumors. It is being developed based on RADR artificial intelligence (AI) and machine learning (ML) platform.

Lantern Pharma overview

Lantern Pharma is a clinical-stage biopharmaceutical company. It develops precision cancer drugs using machine learning techniques, genomic data and precision oncology trials. The company’s pipeline products include LP-100 and LP-184 are non-hormone, non-chemotherapy, DNA Damage Repair (DDR) inhibitors showing multiple cytotoxic effects on tumor cell biology including DNA adduct formation, RNA polymerase stalling and redox protein modification in prostate, ovarian, renal, lung and brain cancers and LP-300 is a first-in-class combination agent indicated for non-small cell lung cancer (NCSLC). Lantern Pharma utilizes Response Algorithm for Drug Positioning & Rescue (RADR) which is an integrated data analytics and machine learning-based platform for patient genetic profiling for robust drug response prediction. The company partners with hospitals, diagnostics, non-profit organizations and universities to accelerate the development of small molecule-based therapies in oncology. Lantern Pharma is headquartered in Dallas, Texas, the US.

For a complete picture of Dimesna’s drug-specific PTSR and LoA scores, buy the report here.

This content was updated on 20 May 2024

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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.