EBTATE is under clinical development by Molecular Targeting Technologies and currently in Phase I for Neuroendocrine Tumors. According to GlobalData, Phase I drugs for Neuroendocrine Tumors have a 74% phase transition success rate (PTSR) indication benchmark for progressing into Phase II. GlobalData’s report assesses how EBTATE’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.

Smarter leaders trust GlobalData

GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.

EBTATE overview

177-Lu-DOTA-EB-TATE is under development for the treatment of neuroendocrine tumors, metastatic gastroenteropancreatic neuroendocrine tumors (GEP-NETs), Hurthle cell thyroid cancer and nasopharyngeal cancer. 177Lu-DOTA-TATE is administered as an intravenous infusion. The drug candidate is a radioconjugate consisting of somatostatin analog octreotide conjugated to radioisotope 177 lutetium via the chelator 1,4,7,10- tetraazacyclododecane-N,N’,N”, N”’-tetraacetic acid (DOTA). The drug candidate acts by targeting Somatostatin Receptor Type 2.

Molecular Targeting Technologies overview

Molecular Targeting Technologies (MT Target) is a biotechnology company that acquires and develops novel technologies for treatment and diagnosis of human diseases. The company offers flow cytometry, small molecule drug conjugates (SMDC), MRI and nuclear imaging agents, optical imaging agents, dyes for bioconjugation, immobilized steroid beads, bioactives, crosslinkers, magnetic beads, blood vessel labelling kits, lipophilic cynanines and custom chemistry services. It develops human anti-rabies monoclonal antibody (Mab) for post-exposure treatment of rabies, which is in phase II clinical stage. The company also offers duramycin and duramycin-nir790 conjugate. MTTI is headquartered in West Chester, Pennsylvania, the US.

For a complete picture of EBTATE’s drug-specific PTSR and LoA scores, buy the report here.

This content was updated on 20 February 2024

Premium Insights

From

The gold standard of business intelligence.

Blending expert knowledge with cutting-edge technology, GlobalData’s unrivalled proprietary data will enable you to decode what’s happening in your market. You can make better informed decisions and gain a future-proof advantage over your competitors.

GlobalData

GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.