Elanco Animal Health has patented interleukin 13 receptor subunit alpha-1/interleukin 4 receptor subunit alpha (IL13R/IL4R) polypeptides for treating IL13 and/or IL4-induced conditions in companion animals. The polypeptides are derived from canines, felines, and equines, with sequences closely matching specific IDs. GlobalData’s report on Elanco Animal Health gives a 360-degree view of the company including its patenting strategy. Buy the report here.
According to GlobalData’s company profile on Elanco Animal Health, NSAID cancer drugs was a key innovation area identified from patents. Elanco Animal Health's grant share as of May 2024 was 43%. Grant share is based on the ratio of number of grants to total number of patents.
Polypeptides for treating il13 and il4-induced conditions in animals
A recently granted patent (Publication Number: US11970526B2) discloses a polypeptide with specific amino acid sequences closely related to sequences identified as SEQ ID NO: 13, 14, 15, 16, 17, 18, 19, 20, 21, 28, 29, 30, and 31. The polypeptide may also include post-expression modifications such as glycosylation, sialyation, acetylation, or phosphorylation. Furthermore, the patent claims variations of the polypeptide that exhibit high binding affinity to IL13 and IL4 proteins in companion animal species, with dissociation constants (Kd) of less than 5×10-6 M, as determined by biolayer interferometry.
Moreover, the patent covers pharmaceutical compositions containing the disclosed polypeptides in combination with a pharmaceutically acceptable carrier. These compositions can be formulated in solid or liquid forms, providing potential applications in the development of therapeutic agents targeting IL13 and IL4 pathways in companion animals. The patent's detailed claims outline the specific amino acid sequences, modifications, and binding properties of the polypeptides, offering valuable insights for researchers and developers in the field of veterinary medicine and biopharmaceuticals.
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