Endo International’s patent involves recombinant nucleic acid and polypeptides encoding collagenase I and collagenase II for therapeutic use. The invention includes methods for preparation and release of collagenase compositions. Claim 1 specifies a nucleic acid molecule encoding a specific amino acid sequence. GlobalData’s report on Endo International gives a 360-degree view of the company including its patenting strategy. Buy the report here.
According to GlobalData’s company profile on Endo International, was a key innovation area identified from patents. Endo International's grant share as of May 2024 was 55%. Grant share is based on the ratio of number of grants to total number of patents.
Patent granted for recombinant nucleic acid encoding collagenase
The granted patent (Publication Number: US11975054B2) discloses a recombinant nucleic acid molecule comprising a polynucleotide encoding a specific amino acid sequence and a heterologous regulatory sequence. This molecule can also be fused to a marker sequence encoding various polypeptides like GST fusion protein, HA polypeptide from influenza, or a hexa-histidine peptide. Additionally, the patent covers a vector containing this nucleic acid molecule, particularly a plasmid, and a recombinant host cell, which can be selected from various cell types including bacterial, fungal, insect, plant, and mammalian cells.
Furthermore, the patent describes a method for producing collagenase I using the recombinant host cell mentioned earlier. The method involves culturing the host cell under suitable conditions for expressing the polynucleotide and then recovering the collagenase I. This innovative approach provides a practical and efficient way to produce collagenase I, which has various applications in research and industrial processes. The patent's detailed claims outline the specific components and steps involved in this novel method, ensuring clarity and specificity in the protection of the intellectual property associated with this technology.
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