Enitociclib is under clinical development by Vincerx Pharma and currently in the Phase I in clinical pathway. The characteristics of the clinical trial as well as other attributes related to the drug, regulations, and company play a fundamental role in ensuring the likelihood of transition that the drug moves from its current development stage to next.

According to GlobalData, the latest event to affect Enitociclib’s likelihood of approval (LoA) and phase transition for Diffuse Large B-Cell Lymphoma took place on 17 Oct 2022, which increased the likelihood that the drug progresses to the next phase in its clinical pathway and increased the likelihood of final approval for this indication.

GlobalData uses proprietary data and analytics to provide a complete picture of this assessment in their Enitociclib Likelihood of Approval (LoA) and Phase Transition Success Rate (PTSR) Report.

Enitociclib overview

Enitociclib is under development for the treatment of refractory solid tumor like tumor agnostic MYC aberrations, mantle cell lymphoma, follicular lymphoma, diffuse large B-cell lymphoma, hematological tumor, melanoma, primary mediastinal b-cell lymphoma, gastrointestinal tract cancer, endometrial cancer, ovarian cancer, triple-negative breast cancer, hormone refractory (castration resistant, androgen-independent) prostate cancer,  relapsed chronic lymphocytic leukemia (CLL), refractory chronic lymphocytic leukemia (CLL), richter's syndrome (RS), non-Hodgkin’s lymphoma (NHL), multiple myeloma, endometrial, vulva, cervical cancer and various other hematological tumors. It is administered as an intravenous infusion. The drug candidate acts by targeting Cyclin Dependent Kinase 9 (CDK9).

Vincerx Pharma overview

Vincera Pharma Inc (Vincera), formerly LifeSci Acquisition Corp, is a clinical stage biopharmaceutical company. It discovers and develops therapies for the treatment of cancer. The company’s pipeline product candidates include VIP152, a CDK9 Inhibitor for solid tumors, non-Hodgkin lymphoma and acute myeloid leukemia; VIP236 for the treatment of multiple solid tumors; VIP943, a KSP inhibitor against leukemia’s; VIP924, an antibody-drug conjugate to treat B-cell malignancies. The company is evaluating therapeutics programs for solid and hematologic tumors. Vincera utilizes its proprietary bio conjugate platform to develop therapies in the areas of oncology. Vincera is headquartered in Santa Clara, California, the US.

Quick View Enitociclib LOA Data

Report Segments
  • Innovator
Drug Name
  • Enitociclib
Administration Pathway
  • Intravenous
Therapeutic Areas
  • Oncology
Key Developers
Highest Development Stage
  • Phase I

GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in its clinical pathway (PTSR), as well as how likely the drug will be approved (LoA). This is based on a proprietary algorithm built from the drugs’ sales forecast, regulatory milestones, cost forecasts, WACC rate and other proprietary data sources found on GlobalData’s Pharmaceutical Intelligence Center.