ERSM-5404 is under clinical development by Hibercell and currently in Phase I for Renal Cell Carcinoma. According to GlobalData, Phase I drugs for Renal Cell Carcinoma have a 74% phase transition success rate (PTSR) indication benchmark for progressing into Phase II. GlobalData’s report assesses how ERSM-5404’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.

GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.

ERSM-5404 overview

ERSM-5404 is under development for the treatment of solid tumors including renal cell carcinoma (clear/papillary), HER2 positive metastatic breast cancer, gastric cancer, small cell lung cancer, non-small cell lung cancer, colorectal cancer, carcinoma of unknown primary, hematological cancers and von hippel-lindau syndrome (VHL). It acts by targeting protein kinase R (PKR)-like ER kinase (PERK). It is being developed based on QuAD3 platform. It is administered through oral route.

Hibercell overview

Hibercell is a biotechnology company that discovers and develops therapies for treatment of cancer. The company is investigating odetiglucan, an immune modulator candidate that enhances immune functions for the treatment of CRC-based liver Metastasis, pancreatic cancer and liver metastasis. It is also developing adaptive stress response modulator programs, HC-5404 for treatment of renal cell carcinoma, gastric cancer and others advanced solid tumors and HC-7366 to treat head and neck, colorectal and bladder cancer. Hibercell is headquartered in New York, the US.

For a complete picture of ERSM-5404’s drug-specific PTSR and LoA scores, buy the report here.

This content was updated on 10 June 2024

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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.