FT-576 is under clinical development by Fate Therapeutics and currently in Phase I for Refractory Multiple Myeloma. According to GlobalData, Phase I drugs for Refractory Multiple Myeloma have a 78% phase transition success rate (PTSR) indication benchmark for progressing into Phase II. GlobalData’s report assesses how FT-576’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.
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GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.
FT-576 overview
FT-576 is under development for the treatment of relapsed / refractor multiple myeloma. The therapeutic candidate constitutes of induced pluripotent stem cell (iPSC)-derived chimeric antigen receptor-B-cell maturation antigen (CAR-BCMA) natural killer (NK) cells expressing, IL-15 receptor and a high-affinity, non-cleavable CD16 (hnCD16) Fc receptor, that are knocked out of CD38 gene. It is developed based on iPSC technology. It is administered through parenteral route.
Fate Therapeutics overview
Fate Therapeutics is a biopharmaceutical company that develops programmed cellular therapies for cancer and immune disorders. The company’s pipeline includes various off-the-shelf, iPSC-derived cellular immunotherapies for the treatment of several hematological malignancies and advanced solid tumors. Its pipeline products also include a donor-derived cell product candidate for the treatment of hematological malignancies. Fate uses its proprietary human-induced pluripotent stem cell (iPSC) platform for product development. The company also has research collaborations with companies, academic centers and medical centers for the advancement of products and technologies. Fate Therapeutics is headquartered in San Diego, California, the US.
For a complete picture of FT-576’s drug-specific PTSR and LoA scores, buy the report here.
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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.
GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.
