GSK has been granted a patent for methods of treating lung cancer by administering a specific dosage of TIM-3 binding agents. The patent outlines a treatment regimen involving a flat dose of 300 mg every 3 weeks, along with an anti-PD-1 antibody. GlobalData’s report on GSK gives a 360-degree view of the company including its patenting strategy. Buy the report here.
According to GlobalData’s company profile on GSK, Human telomerase RT biomarker was a key innovation area identified from patents. GSK's grant share as of February 2024 was 46%. Grant share is based on the ratio of number of grants to total number of patents.
Treatment of lung cancer with tim-3 binding agents
A recently granted patent (Publication Number: US11926665B2) outlines a method for treating lung cancer in human subjects. The method involves administering a flat dose of 300 mg of an anti-TIM-3 antibody and a flat dose of 500 mg of an anti-PD-1 antibody every 3 weeks. The anti-TIM-3 antibody consists of specific heavy and light chain variable domains, while the anti-PD-1 antibody includes distinct heavy and light chain sequences. Additionally, the treatment may include the administration of a chemotherapeutic agent to the patient.
Furthermore, the patent details the specific administration process, suggesting that the anti-TIM-3 antibody should be given to the patient before the anti-PD-1 antibody, with a recommended time gap of either 30 or 45 minutes. Both antibodies are to be administered intravenously, with the anti-TIM-3 antibody potentially being part of a composition for intravenous infusion. The method is particularly focused on treating non-small cell lung cancer in human subjects, emphasizing the importance of the sequence and dosage of the antibodies along with the potential inclusion of a chemotherapeutic agent in the treatment regimen.
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