The Guanine Nucleotide Exchange C9orf72 pipeline drugs market research report outlays comprehensive information on the Guanine Nucleotide Exchange C9orf72 targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA), and molecule type. GlobalData’s report assesses the drugs in the Guanine Nucleotide Exchange C9orf72 pipeline by therapy areas, indications, stages, MoA, RoA, molecule type and the key players in the development pipeline. Buy the report here.
The report also covers products from therapy areas such as Central Nervous System which include the indications Amyotrophic Lateral Sclerosis, and Frontotemporal Dementia (FTD). It also reviews key players involved in Guanine Nucleotide Exchange C9orf72 targeted therapeutics development with respective active and dormant or discontinued products.
The Guanine Nucleotide Exchange C9orf72 pipeline targets constitutes close to 12 molecules. Out of which, approximately 11 molecules are developed by companies and the remaining by the universities/institutes. The molecules developed by companies in Preclinical, and Discovery stages are 8, and 3 respectively. Similarly, the universities portfolio in Discovery comprises 1 molecule.
Guanine Nucleotide Exchange C9orf72 overview
Guanine nucleotide exchange C9orf72 (C9orf72) is a component of the C9orf72-SMCR8 complex, a complex that has guanine nucleotide exchange factor (GEF) activity and regulates autophagy. In the complex, C9orf72 and SMCR8 probably constitute the catalytic subunits that promote the exchange of GDP to GTP, converting inactive GDP-bound RAB8A and RAB39B into their active GTP-bound form, thereby promoting autophagosome maturation.
For a complete picture of Guanine Nucleotide Exchange C9orf72’s drug pipeline, buy the report here.
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