H-3B6545 is under clinical development by H3 Biomedicine and currently in Phase II for Human Epidermal Growth Factor Receptor 2 Negative Breast Cancer (HER2- Breast Cancer). According to GlobalData, Phase II drugs for Human Epidermal Growth Factor Receptor 2 Negative Breast Cancer (HER2- Breast Cancer) have a 49% phase transition success rate (PTSR) indication benchmark for progressing into Phase III. GlobalData’s report assesses how H-3B6545’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.
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GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.
H-3B6545 overview
H-3B6545 is under development for the treatment of locally advanced or metastatic estrogen receptor positive and HER2 negative breast cancer. The drug candidate is administered orally, and it acts by targeting estrogen receptor alpha or ESR1. It is a selective estrogen receptor, covalent antagonist.
H3 Biomedicine overview
H3 Biomedicine, a subsidiary of Eisai Co Ltd, is a biopharmaceutical company that offers therapies. The company concentrates on discovery and early development of novel, targeted anti-cancer compounds. Its products include small-molecule drugs that are developed by utilizing synthetic chemistry approaches and advanced cell-based screening methods. H3 Biomedicine concentrates on scientific approaches and develops new platforms for multiple drug candidate programs. The company leverages the external and internal cumulative investment in cancer genomics to identify therapeutic targets and biomarkers. It operates in the areas of genomics, tumor biology, bioinformatics and innovative synthetic organic chemistry. The company operates through other biotechnology companies for research and development activities and advance cancer treatment options. H3 Biomedicine is headquartered in Cambridge, Massachusetts, the US.
For a complete picture of H-3B6545’s drug-specific PTSR and LoA scores, buy the report here.
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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.
GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.
