H3 mRNA/LNP Vaccine is under clinical development by Sanofi and currently in Phase I for Influenza A Virus, H3N2 Subtype Infections. According to GlobalData, Phase I drugs for Influenza A Virus, H3N2 Subtype Infections have an 89% phase transition success rate (PTSR) indication benchmark for progressing into Phase II. GlobalData’s report assesses how H3 mRNA/LNP Vaccine’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.

GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.

H3 mRNA/LNP Vaccine overview

The vaccine candidate is under development for the prevention of disease caused by H3N2 influenza virus infections in adults aged 18 to 49 Years and 60 Years and above. It comprises of monovalent modified mRNA encoding the full-length hemagglutinin (HA) sequence of A/Tasmania/503/2020 (H3N2) influenza virus encapsulated in lipid nanoparticle (LNP). The vaccine is administered intramuscularly as a suspension.

Sanofi overview

Sanofi is a healthcare company, which is engaged in the discovery, development, manufacturing, and marketing of a wide range of medicines and vaccines. Its portfolio includes medicines for the treatment of cancer, rare diseases, multiple sclerosis; human vaccines for protection against various bacterial and viral diseases; and other products. The company also offers consumer healthcare products for digestion; allergy; cough, cold, flu and sinus; pain; women’s health; and vitamins, minerals, and supplements. Sanofi‘s R&D efforts focus on advancing a combination drug to increase the effectiveness of treatments and on advancing the formulation of new biologics to produce precision medicines. It has operations in Europe, the Americas, Asia-Pacific, Africa, and the Middle East. Sanofi is headquartered in Paris, France.

For a complete picture of H3 mRNA/LNP Vaccine’s drug-specific PTSR and LoA scores, buy the report here.

This content was updated on 10 June 2024

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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.