HBI-002 is under clinical development by Hillhurst Biopharmaceuticals and currently in Phase I for Sickle Cell Disease. According to GlobalData, Phase I drugs for Sickle Cell Disease have an 80% phase transition success rate (PTSR) indication benchmark for progressing into Phase II. GlobalData’s report assesses how HBI-002’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.

GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.

HBI-002 overview

Carbon monoxide is under development for the treatment of pulmonary injury from viral infections, sickle cell disease, Parkinson's disease, concussion (brain injury), ulcerative colitis, acute ischemic stroke, kidney transplant rejection and doxorubicin related cardiotoxicity. It is administered through oral route. The drug candidate acts by targeting heme oxygenase metabolic pathway. It was also under development for the treatment of multiple sclerosis.

For a complete picture of HBI-002’s drug-specific PTSR and LoA scores, buy the report here.

This content was updated on 15 September 2023

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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.