IDE-161 is a small molecule commercialized by Ideaya Biosciences, with a leading Phase II program in Metastatic Ovarian Cancer. According to Globaldata, it is involved in 2 clinical trials, of which 1 is ongoing, and 1 is planned. GlobalData uses proprietary data and analytics to provide a complete picture of IDE-161’s valuation in its risk-adjusted NPV model (rNPV). Buy the model here.

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The revenue for IDE-161 is expected to reach an annual total of $52 mn by 2036 globally based off GlobalData’s Expiry Model. The drug’s revenue forecasts along with estimated costs are used to measure the value of an investment opportunity in that drug, otherwise known as net present value (NPV). Applying the drug’s phase transition success rate to remaining R&D costs and likelihood of approval (LoA) to sales related costs provides a risk-adjusted NPV model (rNPV). The rNPV model is a more conservative valuation measure that accounts for the risk of a drug in clinical development failing to progress.

IDE-161 Overview

IDE-161 is under development for the treatment of solid tumors such as HER2- negative breast cancer, prostate cancer, colorectal cancer, gastric cancer, endometrial cancer, colon cancer and metastatic ovarian cancer. The drug candidate act by targeting poly (ADP ribose) glycohydrolase (PARG). It is administered by oral route.

Ideaya Biosciences Overview

Ideaya Biosciences (Ideaya) is a precision medicine company that develops oncology therapeutics. The company’s product pipeline includes darovasertib (IDE196), a protein kinase C (PKC) inhibitor that targets cancers with GNAQ and GNA11 mutations. It develops small molecule inhibitors based on synthetic lethality against known and novel targets. Ideaya also provides solutions for treating tumors with genetic mutations in homologous recombination deficiency(HRD) and high microsatellite instability (MSI). The company collaborates with Novartis Institute for Biomedical Research, Pfizer Inc, Boston Children’s Hospital, Cancer Research UK, and other academic and research institutes for cancer biology, immunology, and small molecule drug discovery. Ideaya is headquartered in South San Francisco, California, the US.
The company reported revenues of (US Dollars) US$23.4 million for the fiscal year ended December 2023 (FY2023), a decrease of 54.1% over FY2022. The operating loss of the company was US$134.4 million in FY2023, compared to an operating loss of US$62.5 million in FY2022. The net loss of the company was US$113 million in FY2023, compared to a net loss of US$58.7 million in FY2022.

For a complete picture of IDE-161’s valuation, buy the drug’s risk-adjusted NPV model (rNPV) here.

This content was updated on 10 June 2024

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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

To create this model, GlobalData takes into account factors including patent law, known and projected regulatory approval processes, cash flows, drug margins and company expenses. Combining these data points with GlobalData’s world class analysis creates high value models that companies can use to help in evaluation processes for each drug or company.

The rNPV method integrates the probability of a drug reaching a clinical stage into the cash flow at that time, which provides a more accurate valuation, as it considers the probability that the drug never makes it through the clinical pathway to commercialization. GlobalData’s rNPV model uses proprietary likelihood of approval (LoA) and phase transition success rate (PTSR) data for the indication in the highest development stage, which can be found on GlobalData’s Pharmaceutical Intelligence Center.