The pharmaceutical industry continues to be a hotbed of patent innovation. Activity is driven by the evolution of treatment paradigms, and the gravity of unmet needs, as well as the growing importance of technologies such as pharmacogenomics, digital therapeutics, and artificial intelligence. In the last three years alone, there have been over 787,000 patents filed and granted in the pharmaceutical industry, according to GlobalData’s report on Cell & gene therapy in pharma: iPSCsBuy the report here.

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According to GlobalData’s Technology Foresights, which uses over 668,000 patents to analyze innovation intensity for the pharmaceutical industry, there are 80+ innovation areas that will shape the future of the industry.

iPSCs is a key innovation area in cell & gene therapy

Induced pluripotent stem cells (iPSCs) are a type of stem cell that can be generated directly from adult cells, such as skin cells or blood cells, by using defined factors such as transcription factors. These cells can differentiate into any type of cell in the body, making them a potentially powerful tool for regenerative medicine.

GlobalData’s analysis also uncovers the companies at the forefront of each innovation area and assesses the potential reach and impact of their patenting activity across different applications and geographies.  According to GlobalData, there are 100+ companies, spanning technology vendors, established pharmaceutical companies, and up-and-coming start-ups engaged in the development and application of iPSCs.

Key players in iPSCs – a disruptive innovation in the pharmaceutical industry

‘Application diversity’ measures the number of applications identified for each patent. It broadly splits companies into either ‘niche’ or ‘diversified’ innovators.   

‘Geographic reach’ refers to the number of countries each patent is registered in. It reflects the breadth of geographic application intended, ranging from ‘global’ to ‘local’.  

Patent volumes related to iPSCs

Company Total patents (2021 - 2023) Premium intelligence on the world's largest companies
Fujifilm 175 Unlock Company Profile
I'rom Group 51 Unlock Company Profile
Allele Biotechnology and Pharmaceuticals 49 Unlock Company Profile
Johnson & Johnson 42 Unlock Company Profile
Ministry of Trade and Industry, Singapore 42 Unlock Company Profile
BioNTech 36 Unlock Company Profile
Genesis Technologies 35 Unlock Company Profile
Taiga Biotechnologies 34 Unlock Company Profile
Cellscript 34 Unlock Company Profile
BioLamina 33 Unlock Company Profile
I Peace 27 Unlock Company Profile
Lonza Group 26 Unlock Company Profile
ReNeuron Group 24 Unlock Company Profile
Children's Medical Center 21 Unlock Company Profile
National Cancer Center 20 Unlock Company Profile
F. Hoffmann-La Roche 20 Unlock Company Profile
Kangstem Biotech 20 Unlock Company Profile
Mesoblast 17 Unlock Company Profile
Daiichi Sankyo 15 Unlock Company Profile
Mayo Clinic 14 Unlock Company Profile
Bristol-Myers Squibb 13 Unlock Company Profile
New World Laboratories 13 Unlock Company Profile
Megakaryon 13 Unlock Company Profile
Stemlab 12 Unlock Company Profile
Memorial Sloan Kettering Cancer Center 11 Unlock Company Profile
Touchlight Genetics 11 Unlock Company Profile
Hong Guan 11 Unlock Company Profile
Takara 10 Unlock Company Profile
Mclean Hospital 10 Unlock Company Profile
Scripps Health 10 Unlock Company Profile
TRON 10 Unlock Company Profile
Editas Medicine 9 Unlock Company Profile
Centre National de la Recherche Scientifique 9 Unlock Company Profile
Wellcome Trust 8 Unlock Company Profile
Cedars-Sinai Health System 8 Unlock Company Profile
Ibex Biosciences 8 Unlock Company Profile
GC 8 Unlock Company Profile
Orig3N 7 Unlock Company Profile
UAB Research Foundation 7 Unlock Company Profile
General Hospital 7 Unlock Company Profile
Riken 6 Unlock Company Profile
NEW HOPE, CITY OF 6 Unlock Company Profile
Max Planck Society 6 Unlock Company Profile
ReproCELL 6 Unlock Company Profile
Lyell Immunopharma 5 Unlock Company Profile
LifeSci Index Partners 5 Unlock Company Profile
Bayer 5 Unlock Company Profile
Novagenesis 5 Unlock Company Profile
Ono Pharmaceutical 5 Unlock Company Profile
Cerus 4 Unlock Company Profile

Source: GlobalData Patent Analytics

I'rom Group, formerly I'rom Holdings, is a diversified company that offers contract research, clinical trials and regenerative medicine services. The company operates through four business segments. The Site Management Organization (SMO) segment provides support services for contracting or conducting clinical trials. The Contract Research Organization (CRO) segment provides clinical trial operations for pharmaceutical companies and others. The Advanced Medicinal Treatment segment is engaged in the development of gene therapy products, the development, manufacture and sale of products in the field of regenerative medicine based on iPS cells related technologies. The Medical Support segment provides general and comprehensive support for medical business management, such as setting up and renting clinic malls, selling products and related services.

Allele Biotechnology and Pharmaceuticals, and Johnson & Johnson are some of the other key patent filers in iPSCs.

In terms of application diversity, I Peace leads the pack, while Kangstem Biotech and Hong Guan stood in the second and third positions, respectively. By means of geographic reach, BioLamina hed the top position, followed by F. Hoffmann-La Roche and Cellscript.

To further understand the key themes and technologies disrupting the pharmaceutical industry, access GlobalData’s latest thematic research report on Pharmaceutical.

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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

GlobalData’s Patent Analytics tracks patent filings and grants from official offices around the world. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies across the world’s largest industries.