The pharmaceutical industry continues to be a hotbed of innovation, with activity driven by the evolution of new treatment paradigms, and the gravity of unmet needs, as well as the growing importance of technologies such as pharmacogenomics, digital therapeutics, and artificial intelligence. In the last three years alone, there have been over 633,000 patents filed and granted in the pharmaceutical industry, according to GlobalData’s report on Innovation in Pharmaceuticals: Lipase compositions.

However, not all innovations are equal and nor do they follow a constant upward trend. Instead, their evolution takes the form of an S-shaped curve that reflects their typical lifecycle from early emergence to accelerating adoption, before finally stabilising and reaching maturity.

Identifying where a particular innovation is on this journey, especially those that are in the emerging and accelerating stages, is essential for understanding their current level of adoption and the likely future trajectory and impact they will have.

110 innovations will shape the pharmaceutical industry

According to GlobalData’s Technology Foresights, which plots the S-curve for the pharmaceutical industry using innovation intensity models built on over 756,000 patents, there are 110 innovation areas that will shape the future of the industry.

Within the emerging innovation stage, cell therapy for ocular disorders, coronavirus vaccine components, and DNA polymerase compositions are disruptive technologies that are in the early stages of application and should be tracked closely. Adeno-associated virus vectors, alcohol dehydrogenase compositions, and antibody serum stabilisers are some of the accelerating innovation areas, where adoption has been steadily increasing. Among maturing innovation areas are anti-influenza antibody compositions and anti-interleukin-1, which are now well established in the industry.

Innovation S-curve for the pharmaceutical industry

Lipase compositions is a key innovation area in pharmaceuticals

Lipases belong to a class of hydrolase enzymes, which help in the hydrolysis of triglycerides and break them down into free fatty acids and glycerol. They are used as biocatalysts in pharmaceutical production, such as polymer synthesis, cosmetics, flavouring agents, and similar.

GlobalData’s analysis also uncovers the companies at the forefront of each innovation area and assesses the potential reach and impact of their patenting activity across different applications and geographies. According to GlobalData, there are 60+ companies, spanning technology vendors, established pharmaceutical companies, and up-and-coming start-ups engaged in the development and application of lipase compositions.

Key players in lipase compositions – a disruptive innovation in the pharmaceutical industry

‘Application diversity’ measures the number of different applications identified for each relevant patent and broadly splits companies into either ‘niche’ or ‘diversified’ innovators.

‘Geographic reach’ refers to the number of different countries each relevant patent is registered in and reflects the breadth of geographic application intended, ranging from ‘global’ to ‘local’.

Patent volumes related to lipase compositions

Company Total patents (2010 - 2021) Premium intelligence on the world's largest companies
Novo Nordisk Foundation 340 Unlock company profile
Sangamo Therapeutics 164 Unlock company profile
Corteva 147 Unlock company profile
Royal DSM 129 Unlock company profile
E. Merck 113 Unlock company profile
Cellectis 85 Unlock company profile
Massachusetts General Hospital 84 Unlock company profile
DuPont de Nemours 69 Unlock company profile
Factor Bioscience 62 Unlock company profile
General Hospital 60 Unlock company profile
Les Laboratoires Servier 39 Unlock company profile
Precision Biosciences 37 Unlock company profile
Pfizer 35 Unlock company profile
Precigen 35 Unlock company profile
Amano Enzyme 32 Unlock company profile
BASF 30 Unlock company profile
Spogen Biotech 30 Unlock company profile
Caribou Biosciences 26 Unlock company profile
Editas Medicine 25 Unlock company profile
Danaher 23 Unlock company profile
Alcresta Therapeutics 23 Unlock company profile
AbbVie 23 Unlock company profile
CRISPR Therapeutics 21 Unlock company profile
Marubeni 21 Unlock company profile
Vir Biotechnology 21 Unlock company profile
Amgen 18 Unlock company profile
Laboratoires Mayoly Spindler 18 Unlock company profile
Regeneron Pharmaceuticals 17 Unlock company profile
bluebird bio 16 Unlock company profile
Bayer 16 Unlock company profile
Transbiodiesel 16 Unlock company profile
Qingdao Vland Biotech Group 15 Unlock company profile
Ginkgo Bioworks Holdings 14 Unlock company profile
Thermo Fisher Scientific 14 Unlock company profile
Aposense 14 Unlock company profile
TotalEnergies 13 Unlock company profile
Carbios 12 Unlock company profile
Guangdong VTR BioTech 11 Unlock company profile
Agilent Technologies 10 Unlock company profile
Clariant 9 Unlock company profile
Perfect Day 8 Unlock company profile
Viridos 8 Unlock company profile
Puratos 8 Unlock company profile
UAB Research Foundation 8 Unlock company profile
Qiagen 8 Unlock company profile
Eastman Chemical 8 Unlock company profile
LG 8 Unlock company profile
Toyobo 7 Unlock company profile
Guangzhou RiboBio 7 Unlock company profile
Kerry Group 7 Unlock company profile

Source: GlobalData Patent Analytics

Novo Nordisk Foundation is a leading patent filer for lipase compositions. The company has filed patents for lipase compositions for use in pharmaceutical and other various industries. The company is actively seeking the application of lipase compositions in detergents and developing thermostable formulations.

In terms of application diversity, Pfizer is the top company, followed by Asana BioSciences and Factor Bioscience. By means of geographic reach, Les Laboratoires Servier holds the top position. Massachusetts General Hospital and Laboratoires Mayoly Spindler are in the second and third position, respectively.   

To further understand the key themes and technologies disrupting the pharmaceutical industry, access GlobalData’s latest thematic research report on Pharmaceutical.


GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

GlobalData’s Patent Analytics tracks patent filings and grants from official offices around the world. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies across the world’s largest industries.