The pharmaceutical industry continues to be a hotbed of patent innovation. Activity is driven by the evolution of new treatment paradigms, and the gravity of unmet needs, as well as the growing importance of technologies such as pharmacogenomics, digital therapeutics, and artificial intelligence. In the last three years alone, there have been over 787,000 patents filed and granted in the pharmaceutical industry, according to GlobalData’s report on Innovation in pharma: lipase compositions. Buy the report here.
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However, not all innovations are equal and nor do they follow a constant upward trend. Instead, their evolution takes the form of an S-shaped curve that reflects their typical lifecycle from early emergence to accelerating adoption, before finally stabilizing and reaching maturity.
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Identifying where a particular innovation is on this journey, especially those that are in the emerging and accelerating stages, is essential for understanding their current level of adoption and the likely future trajectory and impact they will have.
80+ innovations will shape the pharmaceutical industry
According to GlobalData’s Technology Foresights, which plots the S-curve for the pharmaceutical industry using innovation intensity models built on over 668,000 patents, there are 80+ innovation areas that will shape the future of the industry.
Within the emerging innovation stage, engineered multispecific antibodies, tyrosine kinase inhibitors, and mutant DNA polymerases are disruptive technologies that are in the early stages of application and should be tracked closely. Phenotypic drug screening, antibody-drug conjugates, and polysaccharide-protein conjugate vaccines are some of the accelerating innovation areas, where adoption has been steadily increasing. Among maturing innovation areas are drug delivery nanoparticles and antibody encoding polynucleotide libraries, which are now well established in the industry.
Innovation S-curve for the pharmaceutical industry
Lipase compositions is a key innovation area in pharmaceutical industry
Lipases belong to a class of hydrolase enzymes, which help in the hydrolysis of triglycerides and break them down into free fatty acids and glycerol. They are used as biocatalysts in pharmaceutical production, such as polymer synthesis, cosmetics, flavouring agents, and similar.
GlobalData’s analysis also uncovers the companies at the forefront of each innovation area and assesses the potential reach and impact of their patenting activity across different applications and geographies. According to GlobalData, there are 150+ companies, spanning technology vendors, established pharmaceutical companies, and up-and-coming start-ups engaged in the development and application of lipase compositions.
Key players in lipase compositions – a disruptive innovation in the pharmaceutical industry
‘Application diversity’ measures the number of applications identified for each patent. It broadly splits companies into either ‘niche’ or ‘diversified’ innovators.
‘Geographic reach’ refers to the number of countries each patent is registered in. It reflects the breadth of geographic application intended, ranging from ‘global’ to ‘local’.
Patent volumes related to lipase compositions
| Company | Total patents (2010 - 2022) | Premium intelligence on the world's largest companies |
| Novo Nordisk Foundation | 424 | Unlock Company Profile |
| Sangamo Therapeutics | 182 | Unlock Company Profile |
| E. Merck | 171 | Unlock Company Profile |
| DSM-Firmenich | 163 | Unlock Company Profile |
| Royal DSM | 163 | Unlock Company Profile |
| Corteva | 122 | Unlock Company Profile |
| Massachusetts General Hospital | 115 | Unlock Company Profile |
| Cellectis | 100 | Unlock Company Profile |
| DuPont de Nemours | 81 | Unlock Company Profile |
| Factor Bioscience | 72 | Unlock Company Profile |
| Precision Biosciences | 69 | Unlock Company Profile |
| General Hospital | 68 | Unlock Company Profile |
| Amano Enzyme | 48 | Unlock Company Profile |
| Pfizer | 44 | Unlock Company Profile |
| Alcresta Therapeutics | 42 | Unlock Company Profile |
| Les Laboratoires Servier | 42 | Unlock Company Profile |
| Precigen | 37 | Unlock Company Profile |
| Caribou Biosciences | 36 | Unlock Company Profile |
| Spogen Biotech | 32 | Unlock Company Profile |
| Editas Medicine | 32 | Unlock Company Profile |
| Shionogi | 32 | Unlock Company Profile |
| Verneuil Participations | 26 | Unlock Company Profile |
| Regeneron Pharmaceuticals | 25 | Unlock Company Profile |
| Danaher | 25 | Unlock Company Profile |
| Amgen | 24 | Unlock Company Profile |
| AbbVie | 22 | Unlock Company Profile |
| Vir Biotechnology | 21 | Unlock Company Profile |
| CRISPR Therapeutics | 20 | Unlock Company Profile |
| Ginkgo Bioworks | 20 | Unlock Company Profile |
| Qingdao Vland Biotech Group | 20 | Unlock Company Profile |
| Laboratoires Mayoly Spindler | 18 | Unlock Company Profile |
| Aposense | 18 | Unlock Company Profile |
| Marubeni | 18 | Unlock Company Profile |
| Transbiodiesel | 17 | Unlock Company Profile |
| Carbios | 16 | Unlock Company Profile |
| Thermo Fisher Scientific | 15 | Unlock Company Profile |
| Uni-President China | 15 | Unlock Company Profile |
| Biocad | 15 | Unlock Company Profile |
| Covestro | 14 | Unlock Company Profile |
| TotalEnergies | 14 | Unlock Company Profile |
| Arcadia Biosciences | 14 | Unlock Company Profile |
| POET Research | 14 | Unlock Company Profile |
| Wilmar International | 12 | Unlock Company Profile |
| Perfect Day | 12 | Unlock Company Profile |
| Agilent Technologies | 11 | Unlock Company Profile |
| Puratos | 11 | Unlock Company Profile |
| Guangdong VTR BioTech | 11 | Unlock Company Profile |
| The Procter & Gamble | 10 | Unlock Company Profile |
| Chr. Hansen | 10 | Unlock Company Profile |
| Armata Pharmaceuticals | 10 | Unlock Company Profile |
Source: GlobalData Patent Analytics
Novo Nordisk Foundation is a leading patent filer for lipase compositions. The company has filed patents for lipase compositions for use in pharmaceutical and other various industries. The company is actively seeking the application of lipase compositions in detergents and developing thermostable formulations.
In terms of application diversity, Pfizer is the top company, followed by Les Laboratoires Servier and Factor Bioscience. By means of geographic reach, E. Merck holds the top position. Factor Bioscience and Pfizer are in second and third positions, respectively.
To further understand the key themes and technologies disrupting the pharmaceutical industry, access GlobalData’s latest thematic research report on Pharmaceutical.
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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.
GlobalData’s Patent Analytics tracks patent filings and grants from official offices around the world. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies across the world’s largest industries.
