The pharmaceutical industry continues to be a hotbed of patent innovation. Activity is driven by the evolution of new treatment paradigms, and the gravity of unmet needs, as well as the growing importance of technologies such as pharmacogenomics, digital therapeutics, and artificial intelligence. In the last three years alone, there have been over 787,000 patents filed and granted in the pharmaceutical industry, according to GlobalData’s report on Innovation in pharma: lipase compositionsBuy the report here.

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However, not all innovations are equal and nor do they follow a constant upward trend. Instead, their evolution takes the form of an S-shaped curve that reflects their typical lifecycle from early emergence to accelerating adoption, before finally stabilizing and reaching maturity.

Identifying where a particular innovation is on this journey, especially those that are in the emerging and accelerating stages, is essential for understanding their current level of adoption and the likely future trajectory and impact they will have.

80+ innovations will shape the pharmaceutical industry

According to GlobalData’s Technology Foresights, which plots the S-curve for the pharmaceutical industry using innovation intensity models built on over 668,000 patents, there are 80+ innovation areas that will shape the future of the industry.

Within the emerging innovation stage, engineered multispecific antibodies, tyrosine kinase inhibitors, and mutant DNA polymerases are disruptive technologies that are in the early stages of application and should be tracked closely. Phenotypic drug screening, antibody-drug conjugates, and polysaccharide-protein conjugate vaccines are some of the accelerating innovation areas, where adoption has been steadily increasing. Among maturing innovation areas are drug delivery nanoparticles and antibody encoding polynucleotide libraries, which are now well established in the industry.

Innovation S-curve for the pharmaceutical industry

Lipase compositions is a key innovation area in pharmaceutical industry

Lipases belong to a class of hydrolase enzymes, which help in the hydrolysis of triglycerides and break them down into free fatty acids and glycerol. They are used as biocatalysts in pharmaceutical production, such as polymer synthesis, cosmetics, flavouring agents, and similar.

GlobalData’s analysis also uncovers the companies at the forefront of each innovation area and assesses the potential reach and impact of their patenting activity across different applications and geographies. According to GlobalData, there are 150+ companies, spanning technology vendors, established pharmaceutical companies, and up-and-coming start-ups engaged in the development and application of lipase compositions.

Key players in lipase compositions – a disruptive innovation in the pharmaceutical industry

‘Application diversity’ measures the number of applications identified for each patent. It broadly splits companies into either ‘niche’ or ‘diversified’ innovators.

‘Geographic reach’ refers to the number of countries each patent is registered in. It reflects the breadth of geographic application intended, ranging from ‘global’ to ‘local’.

Patent volumes related to lipase compositions

Company Total patents (2010 - 2022) Premium intelligence on the world's largest companies
Novo Nordisk Foundation 424 Unlock Company Profile
Sangamo Therapeutics 182 Unlock Company Profile
E. Merck 171 Unlock Company Profile
DSM-Firmenich 163 Unlock Company Profile
Royal DSM 163 Unlock Company Profile
Corteva 122 Unlock Company Profile
Massachusetts General Hospital 115 Unlock Company Profile
Cellectis 100 Unlock Company Profile
DuPont de Nemours 81 Unlock Company Profile
Factor Bioscience 72 Unlock Company Profile
Precision Biosciences 69 Unlock Company Profile
General Hospital 68 Unlock Company Profile
Amano Enzyme 48 Unlock Company Profile
Pfizer 44 Unlock Company Profile
Alcresta Therapeutics 42 Unlock Company Profile
Les Laboratoires Servier 42 Unlock Company Profile
Precigen 37 Unlock Company Profile
Caribou Biosciences 36 Unlock Company Profile
Spogen Biotech 32 Unlock Company Profile
Editas Medicine 32 Unlock Company Profile
Shionogi 32 Unlock Company Profile
Verneuil Participations 26 Unlock Company Profile
Regeneron Pharmaceuticals 25 Unlock Company Profile
Danaher 25 Unlock Company Profile
Amgen 24 Unlock Company Profile
AbbVie 22 Unlock Company Profile
Vir Biotechnology 21 Unlock Company Profile
CRISPR Therapeutics 20 Unlock Company Profile
Ginkgo Bioworks 20 Unlock Company Profile
Qingdao Vland Biotech Group 20 Unlock Company Profile
Laboratoires Mayoly Spindler 18 Unlock Company Profile
Aposense 18 Unlock Company Profile
Marubeni 18 Unlock Company Profile
Transbiodiesel 17 Unlock Company Profile
Carbios 16 Unlock Company Profile
Thermo Fisher Scientific 15 Unlock Company Profile
Uni-President China 15 Unlock Company Profile
Biocad 15 Unlock Company Profile
Covestro 14 Unlock Company Profile
TotalEnergies 14 Unlock Company Profile
Arcadia Biosciences 14 Unlock Company Profile
POET Research 14 Unlock Company Profile
Wilmar International 12 Unlock Company Profile
Perfect Day 12 Unlock Company Profile
Agilent Technologies 11 Unlock Company Profile
Puratos 11 Unlock Company Profile
Guangdong VTR BioTech 11 Unlock Company Profile
The Procter & Gamble 10 Unlock Company Profile
Chr. Hansen 10 Unlock Company Profile
Armata Pharmaceuticals 10 Unlock Company Profile

Source: GlobalData Patent Analytics

Novo Nordisk Foundation is a leading patent filer for lipase compositions. The company has filed patents for lipase compositions for use in pharmaceutical and other various industries. The company is actively seeking the application of lipase compositions in detergents and developing thermostable formulations.

In terms of application diversity, Pfizer is the top company, followed by Les Laboratoires Servier and Factor Bioscience. By means of geographic reach, E. Merck holds the top position. Factor Bioscience and Pfizer are in second and third positions, respectively.   

To further understand the key themes and technologies disrupting the pharmaceutical industry, access GlobalData’s latest thematic research report on Pharmaceutical.

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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

GlobalData’s Patent Analytics tracks patent filings and grants from official offices around the world. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies across the world’s largest industries.