The pharmaceutical industry continues to be a hotbed of innovation, with activity driven by the evolution of new treatment paradigms, and the gravity of unmet needs, as well as the growing importance of technologies such as pharmacogenomics, digital therapeutics, and artificial intelligence. In the last three years alone, there have been over 633,000 patents filed and granted in the pharmaceutical industry, according to GlobalData’s report on Innovation in Pharmaceuticals: ssRNA virus peptides. Buy the report here.

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However, not all innovations are equal and nor do they follow a constant upward trend. Instead, their evolution takes the form of an S-shaped curve that reflects their typical lifecycle from early emergence to accelerating adoption, before finally stabilising and reaching maturity.

Identifying where a particular innovation is on this journey, especially those that are in the emerging and accelerating stages, is essential for understanding their current level of adoption and the likely future trajectory and impact they will have.

110 innovations will shape the pharmaceutical industry

According to GlobalData’s Technology Foresights, which plots the S-curve for the pharmaceutical industry using innovation intensity models built on over 756,000 patents, there are 110 innovation areas that will shape the future of the industry.

Within the emerging innovation stage, cell therapy for ocular disorders, coronavirus vaccine components, and DNA polymerase compositions are disruptive technologies that are in the early stages of application and should be tracked closely. Adeno-associated virus vectors, alcohol dehydrogenase compositions, and antibody serum stabilisers are some of the accelerating innovation areas, where adoption has been steadily increasing. Among maturing innovation areas are anti-influenza antibody compositions and anti-interleukin-1, which are now well established in the industry.

Innovation S-curve for the pharmaceutical industry

ssRNA virus peptides is a key innovation area in pharmaceutical

Single-stranded RNA (ssRNA) viruses establish a platform for viral replication in the cytoplasm during the early stages of infection and efficiently generate mature virus. These viruses carry the genetic information to synthesise an RNA-dependent RNA polymerase. SsRNA virus peptide-derived molecules are attractive entities because they can mimic the structural features found in RNA-binding proteins. Peptide-based therapies are versatile, highly efficacious, and have a tolerable side effect profile.

GlobalData’s analysis also uncovers the companies at the forefront of each innovation area and assesses the potential reach and impact of their patenting activity across different applications and geographies. According to GlobalData, there are 180+ companies, spanning technology vendors, established pharmaceutical companies, and up-and-coming start-ups engaged in the development and application of ssRNA virus peptides.

Key players in ssRNA virus peptides – a disruptive innovation in the pharmaceutical industry

‘Application diversity’ measures the number of different applications identified for each relevant patent and broadly splits companies into either ‘niche’ or ‘diversified’ innovators.

‘Geographic reach’ refers to the number of different countries each relevant patent is registered in and reflects the breadth of geographic application intended, ranging from ‘global’ to ‘local’.

Patent volumes related to ssRNA virus peptides

Company Total patents (2021 - 2023) Premium intelligence on the world's largest companies
Johnson & Johnson 419 Unlock Company Profile
GSK 419 Unlock Company Profile
C. H. Boehringer Sohn 264 Unlock Company Profile
Sanofi 259 Unlock Company Profile
Mitsubishi Chemical Group 236 Unlock Company Profile
Novavax 208 Unlock Company Profile
Merck & Co 188 Unlock Company Profile
Vertex Pharmaceuticals 157 Unlock Company Profile
Takeda Pharmaceutical 132 Unlock Company Profile
Curevac 107 Unlock Company Profile
United Nations Industrial Development Organization 103 Unlock Company Profile
Pfizer 100 Unlock Company Profile
US Department of Health and Human Services 93 Unlock Company Profile
Autoimmune Technologies 89 Unlock Company Profile
Centre National de la Recherche Scientifique 85 Unlock Company Profile
United States Of America 80 Unlock Company Profile
Bavarian Nordic 72 Unlock Company Profile
Inovio Pharmaceuticals 70 Unlock Company Profile
FluGen 69 Unlock Company Profile
Toray Industries 62 Unlock Company Profile
SEEK Group 61 Unlock Company Profile
Zoetis 58 Unlock Company Profile
St. Jude Children’s Research Hospital 55 Unlock Company Profile
Valneva 54 Unlock Company Profile
CSL 54 Unlock Company Profile
Administrators of Tulane Educational Fund 54 Unlock Company Profile
Altimmune 53 Unlock Company Profile
FDS Pharma LLP 53 Unlock Company Profile
Oswaldo Cruz Foundation 45 Unlock Company Profile
Compagnie Merieux Alliance 44 Unlock Company Profile
European Molecular Biology Laboratory 43 Unlock Company Profile
Abbott Laboratories 43 Unlock Company Profile
TheVax Genetics Vaccine 40 Unlock Company Profile
Fraunhofer-Gesellschaft zur Forderung der Angewandten Forschung 39 Unlock Company Profile
Fastilium Property Group 39 Unlock Company Profile
Grifols 38 Unlock Company Profile
Bio-Rad Laboratories 38 Unlock Company Profile
Theraclone Sciences 38 Unlock Company Profile
Precigen 36 Unlock Company Profile
Gilead Sciences 35 Unlock Company Profile
VLP Therapeutics 34 Unlock Company Profile
Solon Eiendom 34 Unlock Company Profile
F. Hoffmann-La Roche 33 Unlock Company Profile
Longhorn Vaccines and Diagnostics 31 Unlock Company Profile
Xiamen Innovax Biotech 30 Unlock Company Profile
BrightPath Biotherapeutics 30 Unlock Company Profile
Trustee for Horizon 29 Unlock Company Profile
Folia Biotech 29 Unlock Company Profile
Erasmus MC 28 Unlock Company Profile
Quidel 26 Unlock Company Profile

Source: GlobalData Patent Analytics

Johnson & Johnson (J&J) is the leading patent filer in ssRNA virus peptides. J&J develops, manufactures, and sells pharmaceutical products, medical devices, and consumer products. The company provides pharmaceuticals for immune diseases, cancer, neurological disorders, infectious, cardiovascular, and metabolic diseases; consumer products in oral care, baby care, beauty, over the counter (OTC) medicines, women’s health, and wound care categories; and medical devices for use in the cardiovascular, orthopaedic, neurovascular, general surgery, and vision care fields. J&J is headquartered in New Brunswick, New Jersey, US.

GSK and C. H. Boehringer Sohn are the other key patent filers in ssRNA virus peptides.

In terms of application diversity, Eiger BioPharmaceuticals is the top company, followed by Mymetics and Amplia Therapeutics. By means of geographic reach, Artificial Cell Technologies holds the top position. While Cilian and Mymetics stand in second and third positions, respectively.

To further understand the key themes and technologies disrupting the pharmaceutical industry, access GlobalData’s latest thematic research report on Pharmaceutical.

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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

GlobalData’s Patent Analytics tracks patent filings and grants from official offices around the world. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies across the world’s largest industries.