L-130 is under clinical development by Lobe Sciences and currently in Phase I for Anxiety Disorders. According to GlobalData, Phase I drugs for Anxiety Disorders have a 68% phase transition success rate (PTSR) indication benchmark for progressing into Phase II. GlobalData’s report assesses how L-130’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.

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GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.

L-130 overview

L-130 is under development for the treatment of severe anxiety disorders and cluster headache. It is a synthetic analogue of psilocin and acts by targeting 5-hydroxytryptamine receptor 2A (5-HT2A) receptor.

Lobe Sciences overview

Lobe Sciences is engaged in investigation and development of treatments using alternative and nontraditional mechanisms for better health. Lobe Sciences is headquartered in Vancouver, British Columbia, Canada.

For a complete picture of L-130’s drug-specific PTSR and LoA scores, buy the report here.

This content was updated on 10 June 2024

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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.