Levetiracetam ER is under clinical development by AgeneBio and currently in Phase II for Psychosis. According to GlobalData, Phase II drugs for Psychosis have a 50% phase transition success rate (PTSR) indication benchmark for progressing into Phase III. GlobalData’s report assesses how Levetiracetam ER’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.

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GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.

Levetiracetam ER overview

Levetiracetam ER (AGB-101) is under development for the treatment of amnestic mild cognitive impairment (aMCI) due to Alzheimer’s dementia and psychosis. The drug candidate is once-daily, extended-release capsule and tablet formulation of levetiracetam administered through oral route. It acts by targeting synaptic vesicle protein (SV2A) ligand.

AgeneBio overview

AgeneBio is a pharmaceutical company that develops therapies for psychiatric and neurological diseases. The company’s therapy is targeted to prevent neurodegeneration and preserve and restore cognitive function for unserved patients. Its lead candidate AGB101 is under phase 3 of clinical trials for the treatment of mild cognitive impairment (aMCI) and can delay progression to Alzheimer’s dementia and can target hippocampus overactivity. AgeneBio’s other pipeline product is GABAA alpha5 a small molecule program is being developed for the treatment of aMCI, autism and schizophrenia, among others. The company partners with Johns Hopkins University and leading research centers worldwide. AgeneBio is headquartered in Baltimore, Maryland, the US.

For a complete picture of Levetiracetam ER’s drug-specific PTSR and LoA scores, buy the report here.

This content was updated on 7 February 2024

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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.