GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.

Inflammatory Pain overview

Inflammatory pain stems from the body’s response to injury, infection, or autoimmune conditions, activating the immune system and releasing inflammatory molecules. This process triggers pain receptors, leading to localized discomfort, redness, swelling, and warmth. Conditions like arthritis, tendonitis, or infections often induce this type of pain. Inflammatory mediators, such as cytokines, prostaglandins, and histamine, sensitize nerve endings, heightening pain perception. Diagnosis involves assessing the underlying condition and inflammatory markers. Treatment focuses on addressing the cause, managing inflammation through medications (like NSAIDs or corticosteroids), physical therapy, and lifestyle changes, aiming to alleviate pain and reduce inflammation for improved function and comfort.

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GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.