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Data Insights Likelihood of Approval Analysis for Peripheral Neuropathy (Sensory Neuropathy)

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GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.

Peripheral Neuropathy (Sensory Neuropathy) overview

Peripheral neuropathy refers to a condition that involves damage or dysfunction of the peripheral nerves, resulting in various sensory, motor, and autonomic symptoms. These nerves transmit signals between the central nervous system (brain and spinal cord) and the rest of the body, controlling muscle movements, sensation, and organ function. There are different types of peripheral neuropathy, each affecting specific nerves and causing varying symptoms: Sensory neuropathy, motor neuropathy, and autonomic neuropathy. Sensory neuropathy primarily affects sensory nerves, leading to sensations of tingling, numbness, burning, increased sensitivity to touch, sharp or stabbing pains, and difficulty with coordination and balance. It can affect the hands, feet, arms, or legs. Motor neuropathy affects motor nerves, resulting in muscle weakness, loss of coordination, or muscle cramps. Autonomic neuropathy involves nerves regulating involuntary bodily functions, causing symptoms like changes in blood pressure, heart rate, digestion, sweating, and bladder control. Peripheral neuropathy can have various causes. Diabetic neuropathy is one of the most common causes, affecting individuals with uncontrolled or poorly managed diabetes. Accidents, repetitive stress injuries, or trauma can damage nerves. Certain viral or bacterial infections like Lyme disease, HIV/AIDS, or shingles can lead to neuropathy. Exposure to toxins, such as heavy metals, certain medications, or chemicals, can damage nerves. Some forms of neuropathy are inherited.

For a complete picture of PTSR and LoA scores for drugs in Peripheral Neuropathy (Sensory Neuropathy), buy the report here.

GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article. 

GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.