Lonza Group has been granted a patent for a modular system designed for the industrial growth of biologics. The system features interconnected subsystems, including bioreactors and purification units, allowing for flexible process flow and scalable output capacity to accommodate phased growth. GlobalData’s report on Lonza Group gives a 360-degree view of the company including its patenting strategy. Buy the report here.
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According to GlobalData’s company profile on Lonza Group, Nanoemulsion cosmetics was a key innovation area identified from patents. Lonza Group's grant share as of July 2024 was 60%. Grant share is based on the ratio of number of grants to total number of patents.
System for industrial growth of biologics
The granted patent US12071607B2 outlines a sophisticated system designed for the growth of biologics, incorporating a perfusion seed train or a fed-batch bioreactor seed train. The system features at least one perfusion-based reactor that feeds into a bioreactor subsystem, which consists of at least two bioreactors. Each bioreactor is connected to multiple harvest subsystems, each equipped with harvest tanks. Additionally, a purification subsystem is integrated into the system, positioned downstream from the harvest subsystems, with direct access to a maintenance area via airlocks. This configuration allows for efficient processing and management of biologics, with the potential to handle over 100 batches annually and bioreactors of 6000 liters or larger.
Further enhancing the system's functionality, the patent includes provisions for a flow control assembly that regulates fluid flow between bioreactors and harvest subsystems. The design also accommodates multiple purification subsystems, enabling the production of different biologics in parallel. The purification subsystem may include various components such as chromatography column stations, pre-viral and post-viral trains, and the ability to transfer chromatography columns between these trains. This modular approach allows for flexibility and efficiency in the purification process, ensuring that the system can adapt to diverse production needs while maintaining high operational standards.
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GlobalData Patent Analytics tracks bibliographic data, legal events data, point in time patent ownerships, and backward and forward citations from global patenting offices. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies
