MediciNova has been granted a patent for higher dosage oral formulations of ibudilast in tablet or capsule form. The pharmaceutical composition includes specific percentages of ibudilast, lactose, microcrystalline cellulose, hypromellose, magnesium stearate, and colloidal silicon dioxide, with a defined dissolution profile. GlobalData’s report on MediciNova gives a 360-degree view of the company including its patenting strategy. Buy the report here.
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According to GlobalData’s company profile on MediciNova, Peptide pharmacophores was a key innovation area identified from patents. MediciNova's grant share as of January 2024 was 35%. Grant share is based on the ratio of number of grants to total number of patents.
A recently granted patent (Publication Number: US11865214B2) discloses a pharmaceutical composition containing ibudilast, lactose, microcrystalline cellulose, hypromellose, magnesium stearate, and colloidal silicon dioxide. The composition, in the form of a tablet or capsule, is designed to release at least 12% of ibudilast within 2 hours in simulated gastric fluid. Additionally, the tablet may have a coating comprising polyvinyl alcohol, plasticizer, and pigment.
Furthermore, the patent claims variations in the composition, including different percentages of each ingredient, the use of specific excipients like microcrystalline cellulose, lactose, or hypromellose, and the option for the tablet or capsule to release up to 90% of ibudilast within 24 hours under specific testing conditions. The composition may contain ibudilast ranging from 10 mg to 100 mg, with lactose specified as lactose monohydrate in one instance. The patent also mentions the option for the tablet to have a coating and variations in the form of the composition, such as tablets or capsules.
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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.
GlobalData Patent Analytics tracks bibliographic data, legal events data, point in time patent ownerships, and backward and forward citations from global patenting offices. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies
