The Metabotropic Glutamate Receptor 5 pipeline drugs market research report outlays comprehensive information on the Metabotropic Glutamate Receptor 5 targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA), and molecule type. GlobalData’s report assesses the drugs in the Metabotropic Glutamate Receptor 5 pipeline by therapy areas, indications, stages, MoA, RoA, molecule type and the key players in the development pipeline. Buy the report here.
The report also covers products from therapy areas such as Central Nervous System, Genetic Disorders, Ophthalmology, and Undisclosed which include the indications Anxiety Disorders, Substance (Drug) Abuse, Fragile X Syndrome, DiGeorge Syndrome, Blepharospasm, and Unspecified. It also reviews key players involved in Metabotropic Glutamate Receptor 5 targeted therapeutics development with respective active and dormant or discontinued products.
The Metabotropic Glutamate Receptor 5 pipeline targets constitutes close to 17 molecules. Out of which, approximately 12 molecules are developed by companies and the remaining by the universities/institutes. The molecules developed by companies in Phase III, Phase II, Phase I, and Preclinical stages are 1, 4, 3, and 4 respectively. Similarly, the universities portfolio in Preclinical comprises 5 molecule.
Metabotropic Glutamate Receptor 5 overview
Metabotropic glutamate receptor 5 (mGluR5) is a G protein-coupled receptor. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling activates a phosphatidylinositol calcium second messenger system and generates a calcium activated chloride current. mGluR5 plays an important role in the regulation of synaptic plasticity and the modulation of the neural network activity.
For a complete picture of Metabotropic Glutamate Receptor 5’s drug pipeline, buy the report here.
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