MiMedx Group has filed a patent for a method of preparing placenta membrane tissue grafts for medical use. The method involves obtaining a placenta, cleaning it, separating the chorion tissue from the amniotic membrane, dehydrating a selected layer of either the chorion tissue or the amniotic membrane, and cutting it into multiple tissue grafts. The drying fixture used includes grooves or raised edges to define the outer contours of the grafts and raised or indented logos to distinguish the top from the bottom side of the grafts. The grafts can be comprised of single or multiple layers of amnion or chorion, or a combination of both. GlobalData’s report on MiMedx Group gives a 360-degree view of the company including its patenting strategy. Buy the report here.

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According to GlobalData’s company profile on MiMedx Group, cardiothoracic surgery instruments was a key innovation area identified from patents. MiMedx Group's grant share as of June 2023 was 1%. Grant share is based on the ratio of number of grants to total number of patents.

Method for preparing placenta membrane tissue grafts

Source: United States Patent and Trademark Office(USPTO). Credit: MiMedx Group Inc

A recently filed patent (Publication Number: US20230201419A1) describes a method for preparing a dehydrated tissue graft. The method involves several steps, including placing a first chorion tissue layer on a drying fixture, adding additional chorion tissue layers, dehydrating the chorions to produce a dehydrated tissue graft, placing the graft in a package, and sealing the package.

In one embodiment of the method (Claim 22), two or more additional layers of chorion are added during the process. This suggests that the number of chorion tissue layers can be adjusted based on the desired outcome.

Another aspect of the method (Claim 23) involves contacting the first chorion tissue layer and the additional layers with at least one antibiotic prior to the dehydration step. The patent mentions specific antibiotics such as streptomycin sulfate or gentamicin sulfate that can be used in this process.

The package used to store the dehydrated tissue graft is described as a pouch (Claim 25). Additionally, in a specific embodiment (Claim 26), the pouch is an inner pouch that is placed in an outer container. Both the inner pouch and the outer container are sealed to ensure the integrity of the graft.

It is worth noting that the outer container can also be a pouch (Claim 27), indicating that the packaging can be flexible and adaptable to different requirements.

Overall, this patent describes a method for preparing a dehydrated tissue graft that involves specific steps, including the use of antibiotics and a particular packaging process. The method allows for customization by adjusting the number of chorion tissue layers and provides options for packaging the graft.

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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

GlobalData Patent Analytics tracks bibliographic data, legal events data, point in time patent ownerships, and backward and forward citations from global patenting offices. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies