MiMedx Group. has patented a tissue graft derived from the placenta, composed of amnion tissue with the epithelium layer removed to expose the basement layer. The graft allows host cells to interact with bio-active factors, similar to native human tissue like oral mucosa. GlobalData’s report on MiMedx Group gives a 360-degree view of the company including its patenting strategy. Buy the report here.

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According to GlobalData’s company profile on MiMedx Group, Cardiothoracic surgery instruments was a key innovation area identified from patents. MiMedx Group's grant share as of January 2024 was 59%. Grant share is based on the ratio of number of grants to total number of patents.

Tissue graft derived from placenta with exposed basement membrane

Source: United States Patent and Trademark Office (USPTO). Credit: MiMedx Group Inc

A patent application (Publication Number: US20230414670A1) discloses a tissue graft comprising a first membrane made of amnion with additional membranes laminated to it. The first membrane includes an exposed basement membrane and stromal layer, with the additional membranes adjacent to the stromal layer. The graft can consist of various membranes such as amnion, chorion, allograft pericardium, acellular dermis, and others, either individually or in combination. The number of membranes laminated to the first membrane can range from 1 to 10, with a thickness of 0.2 mm to 10 mm. The graft can be used for various medical applications, including wound treatment, dental defects, tissue regeneration, and more.

Furthermore, the patent application describes a method for preparing the tissue graft, involving obtaining a placenta, cleaning it, separating the amnion and chorion layers, removing epithelium cells to expose the basement membrane, laminating additional membranes, and dehydrating the layered tissue graft. The method includes steps such as cleaning the placenta with a hyperisotonic solution, soaking the amnion in an antibiotic solution, physically cleaning the amniotic membrane, and dehydrating the tissue graft on a drying fixture. The prepared tissue graft can be used for various medical procedures, including treating mucosal tissue wounds, dental defects, and other applications. The method provides detailed instructions on preparing the tissue graft, ensuring its effectiveness and safety for medical use.

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GlobalData Patent Analytics tracks bibliographic data, legal events data, point in time patent ownerships, and backward and forward citations from global patenting offices. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies