Navacaprant hydrochloride is under clinical development by Neumora Therapeutics and currently in Phase II for Bipolar II Disorder. According to GlobalData, Phase II drugs for Bipolar II Disorder does not have sufficient historical data to build an indication benchmark PTSR for Phase II. GlobalData uses proprietary data and analytics to create drugs-specific PTSR and LoA in the Navacaprant hydrochloride LoA Report. Buy the report here.
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GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.
Navacaprant hydrochloride overview
Navacaprant hydrochloride is under development for the treatment of bipolar II depression and major depressive disorder (MDD) with anhedonia. The drug candidate is administered through oral route in the form of tablet. It is a small molecule targeting kappa-type opioid receptor (KOR). It is being developed based on AI/ML technology.
Neumora Therapeutics overview
Neumora Therapeutics (Neumora) is a clinical-stage biopharmaceutical company that develops therapies to treat neuropsychiatric and neurodegenerative diseases. The company’s lead product candidate, Navacaprant (NMRA-140), is a novel once-daily oral kappa opioid receptor for treatment of major depressive disorder and bipolar depression. Its pipeline includes various other drug candidates such as NMRA-511, a V1aR antagonist to treat agitation in Alzheimer’s disease; NMRA-266, NMRA-M4R, and NMRA-NMDA for the treatment of schizophrenia. The company is also investigating and developing drugs for Alzheimer’s and Parkinson’s disease treatments. Neumora is headquartered in Watertown, Massachusetts, the US.
For a complete picture of Navacaprant hydrochloride’s drug-specific PTSR and LoA scores, buy the report here.
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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.
GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.
