Nitronazine is under clinical development by Guangzhou Magpie Pharmaceutical and currently in Phase II for Amyotrophic Lateral Sclerosis. According to GlobalData, Phase II drugs for Amyotrophic Lateral Sclerosis have a 65% phase transition success rate (PTSR) indication benchmark for progressing into Phase III. GlobalData’s report assesses how Nitronazine’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.

GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.

Nitronazine overview

Nitronazine is under development for the treatment of  ischemic stroke, type 2 diabetes, diabetic nephropathy, amyotrophic lateral sclerosis, diabetic retinopathy and alport syndrome. The drug candidate is administered through injection and oral routes. It is a nitrone derivative of tetramethylpyrazine derivatives. It acts by targeting AMPK/NRF2 and mTOR.

It was also under development for Parkinson’s disease.

Guangzhou Magpie Pharmaceutical overview

Guangzhou Magpie Pharmaceutical., is a drug developer. The company is headquartered in China.

For a complete picture of Nitronazine’s drug-specific PTSR and LoA scores, buy the report here.

This content was updated on 20 May 2024

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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.