NMRA-M4R is under clinical development by Neumora Therapeutics and currently in Phase I for Schizophrenia. According to GlobalData, Phase I drugs for Schizophrenia have a 66% phase transition success rate (PTSR) indication benchmark for progressing into Phase II. GlobalData’s report assesses how NMRA-M4R’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.

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GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.

NMRA-M4R overview

NMRA-M4R is under development for the treatment of schizophrenia and unspecified psychiatric disorders. The drug candidate is administered through oral route. It is a Positive Allosteric Modulator (PAM) Program and acts by targeting Muscarinic Acetylcholine Receptor M4 (CHRM4). 

Neumora Therapeutics overview

Neumora Therapeutics formerly RBNC Therapeutics, is a biotechnology company that uses data science and neuroscience to develop precision medications to treat brain diseases. Neumora Therapeutics is headquartered in Watertown, Massachusetts, the US.

For a complete picture of NMRA-M4R’s drug-specific PTSR and LoA scores, buy the report here.

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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.