Ociperlimab is under clinical development by BeiGene and currently in Phase III for Squamous Non-Small Cell Lung Cancer. According to GlobalData, Phase III drugs for Squamous Non-Small Cell Lung Cancer have a 42% phase transition success rate (PTSR) indication benchmark for progressing into Pre-Registration. GlobalData’s report assesses how Ociperlimab’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.
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GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.
Ociperlimab overview
Ociperlimab (BGB-A1217) is under development for the treatment of solid tumors including advanced hepatocellular carcinoma, end stage small-cell lung cancer, locally advanced and metastatic non-squamous/squamous non-small cell lung cancer, recurrent or metastatic esophageal squamous cell carcinoma, cervical cancer, recurrent or metastatic HNSCC, gastric/ gastroesophageal adenocarcinoma, relapsed or refractory diffuse large B-cell lymphoma and unspecified indication. The drug candidate is a humanized, IgG1 monoclonal antibody against T cell immunoreceptor with Ig and ITIM domains (TIGIT). It was under development for the treatment of triple negative breast cancer.
BeiGene overview
BeiGene is a biotechnology company. It is specialized in the development and commercialization of immuno-oncology medicines to treat cancers. The company offers BRUKINSA, a BTK (Bruton’s tyrosine kinase) inhibitor against mantle cell lymphoma (MCL). BeiGene also provides Zanubrutinib (BGB-3111), a small molecule inhibitor of BTK to treat B cell malignancies; Tislelizumab (BGB-A317), a monoclonal antibody targeting solid tumors and hematologic cancer; and Pamiparib (BGB-290) against solid tumor malignancies. The company has operations in the US, Australia, Germany, Spain, Switzerland, and Italy. BeiGene is headquartered in Grand Cayman, Cayman Islands.
For a complete picture of Ociperlimab’s drug-specific PTSR and LoA scores, buy the report here.
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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.
GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.
