Ono Pharmaceutical has been granted a patent for a drug containing a compound with agonistic activity to STING, represented by formula (I-1). The compound can be used to suppress cancer or infectious disease progression, recurrence, or treatment. GlobalData’s report on Ono Pharmaceutical gives a 360-degree view of the company including its patenting strategy. Buy the report here.

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According to GlobalData’s company profile on Ono Pharmaceutical, Peptide pharmacophores was a key innovation area identified from patents. Ono Pharmaceutical's grant share as of February 2024 was 46%. Grant share is based on the ratio of number of grants to total number of patents.

Compound for treating cancer or infectious disease

Source: United States Patent and Trademark Office (USPTO). Credit: Ono Pharmaceutical Co Ltd

A recently granted patent (Publication Number: US11919917B2) discloses a compound of formula (I-1) and its pharmaceutically acceptable salt or solvate. The compound includes a benzene ring or a monocyclic aromatic heterocycle with heteroatoms like oxygen, nitrogen, or sulfur. Additionally, the compound may have specific structural features, such as Z being an oxygen atom or X being a nitrogen atom with Y as C—H. The patent covers various derivatives of the compound, including those with specific ring structures like pyrazole, triazole, or imidazole.

Furthermore, the patent encompasses pharmaceutical compositions containing the disclosed compound, along with a carrier, for potential use in suppressing colon cancer progression or stimulating STING in subjects. The method involves administering the compound to the subject, either alone or in combination with anti-cancer drugs like anti-PD-1 or anti-PD-L1 antibodies. Additionally, the patent includes claims for specific alkali metal salts or solvates of the compound, highlighting the potential versatility and applications of the disclosed invention in the field of oncology and immunotherapy.

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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

GlobalData Patent Analytics tracks bibliographic data, legal events data, point in time patent ownerships, and backward and forward citations from global patenting offices. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies