OR-502 is under clinical development by OncoResponse and currently in Phase II for Ovarian Cancer. According to GlobalData, Phase II drugs for Ovarian Cancer have a 26% phase transition success rate (PTSR) indication benchmark for progressing into Phase III. GlobalData’s report assesses how OR-502’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.
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GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.
OR-502 overview
OR-502 is under development for the treatment of melanoma, sarcoma, cutaneous squamous cell carcinoma (CSCC), ovarian cancer. The drug candidate is fully humanized monoclonal antibody and is being developed based on Theraclone's I-STAR technology platform. It acts by targeting LILRB2 (leukocyte immunoglobulin-like receptor subfamily B member 2). It is administered through intravenous route.
OncoResponse overview
OncoResponse is an immuno-oncology company focused on the discovery, development, and commercialization of novel antibodies against cancer targets. The company’s lead program includes ONCR-201, an anti-EMP2 fully-human monoclonal antibody being developed for female malignancies treatment. Its proprietary human-antibody discovery platform enables to identify antibodies made by Elite Responders that modulate myeloid cells in the tumor micro environment. OncoResponse works in partnership with MD Anderson Cancer Center, Theraclone Sciences, Oregon Health and Science University and William Marsh Rice University to develop its pipeline products. The company is funded by Canaan Partners, Arc Venture Partners, Bering, GreatPoint Ventures and Helsinn Investment Fund. OncoResponse is headquartered in Seattle, Washington, the US.
For a complete picture of OR-502’s drug-specific PTSR and LoA scores, buy the report here.
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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.
GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.
