PSC-100 is under clinical development by Celularity and currently in Phase I for Acute Lymphocytic Leukemia (ALL, Acute Lymphoblastic Leukemia). According to GlobalData, Phase I drugs for Acute Lymphocytic Leukemia (ALL, Acute Lymphoblastic Leukemia) have a 73% phase transition success rate (PTSR) indication benchmark for progressing into Phase II. GlobalData’s report assesses how PSC-100’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.

GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.

PSC-100 overview

PSC-100 is under development for the treatment of severe hypoxic-ischemic encephalopathy, adrenoleukodystrophy (ALD), acute lymphoblastic leukemia (ALL) and pulmonary inflammation. It is administered intravenously. The drug candidate comprised of human placental-derived stem cells (HPDSC).

Celularity overview

Celularity is a biotechnology company that develops and commercializes therapeutics derived from the placenta for autoimmune and degenerative diseases, immuno-oncology, and functional regeneration. The company’s pre-clinical and clinical assets include CAR-T cell receptor and CAR-NK products; and functional regeneration products for wounds, burns, orthopedic, and other surgical indications. It also provides cord blood and placental blood and tissue biosourcing options. Celularity harnesses allogeneic placental cell platform to develop its product portfolio. The company’s products find application in the treatment of acute myeloid leukemia, crohn’s disease, diabetic peripheral neuropathy, and oral and aesthetic tissue repair among others. Celularity is headquartered in Warren, New Jersey, the US.

For a complete picture of PSC-100’s drug-specific PTSR and LoA scores, buy the report here.

GlobalData

GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in its clinical pathway (PTSR), as well as how likely the drug will be approved (LoA). This is based on a proprietary algorithm built from the drugs’ sales forecast, regulatory milestones, cost forecasts, WACC rate and other proprietary data sources found on GlobalData’s Pharmaceutical Intelligence Center.