PTC Therapeutics has been granted a patent for compounds, forms, and pharmaceutical compositions for treating Huntington’s disease. The patent specifically covers substituted bicyclic heterocyclic and heteroaryl compounds of Formula (I). GlobalData’s report on PTC Therapeutics gives a 360-degree view of the company including its patenting strategy. Buy the report here.

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According to GlobalData’s company profile on PTC Therapeutics, Human telomerase RT biomarker was a key innovation area identified from patents. PTC Therapeutics's grant share as of February 2024 was 37%. Grant share is based on the ratio of number of grants to total number of patents.

A recently granted patent (Publication Number: US11858941B2) discloses a compound of Formula (Ibbl) and its various forms, with R1 being a heterocyclyl group selected from a list of options. The patent also covers compounds where R2 is phenyl, potentially substituted with specific substituents. Additionally, the patent includes compounds in the form of salts such as hydrochloride, hydrobromide, formate, dihydrochloride, and dihydrobromide salts.

Furthermore, the patent describes methods for treating or ameliorating Huntington's Disease (HD) by administering the disclosed compounds to a subject in need. The effective amount of the compound or its form is specified to be in a range from about 0.001 mg/kg/day to about 500 mg/kg/day. The patent also includes pharmaceutical compositions containing the disclosed compounds along with pharmaceutically acceptable excipients, providing a comprehensive approach to the treatment of HD through different formulations and administration methods.

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GlobalData Patent Analytics tracks bibliographic data, legal events data, point in time patent ownerships, and backward and forward citations from global patenting offices. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies